Modulation of Inflammation and Immune Responses by Heme Oxygenase-1: Implications for Infection with Intracellular Pathogens

by Diego L. Costa, Eduardo P. Amaral, Bruno B. Andrade, Alan Sher
Published 2020-11-01

Dissecting Major Signaling Pathways throughout the Development of Prostate Cancer

by Henrique B. da Silva, Eduardo P. Amaral, Eduardo L. Nolasco, Nathalia C. de Victo, Rodrigo Atique, Carina C. Jank, Valesca Anschau, Luiz F. Zerbini, Ricardo G. Correa
Published 2013-01-01

Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes

by Diego L. Costa, Sivaranjani Namasivayam, Eduardo P. Amaral, Kriti Arora, Alex Chao, Lara R. Mittereder, Mamoudou Maiga, Helena I. Boshoff, Clifton E. Barry, Celia W. Goulding, Bruno B. Andrade, Alan Sher
Published 2016-10-01

Combining Host Genetics and Functional Analysis to Depict Inflammasome Contribution in Tuberculosis Susceptibility and Outcome in Endemic Areas

by Dhêmerson Souza De Lima, Caio C. B. Bomfim, Vinícius N. C. Leal, Edione C. Reis, Jaíne L. S. Soares, Fernanda P. Fernandes, Eduardo P. Amaral, Flavio V. Loures, Mauricio M. Ogusku, Maria R. D'Imperio Lima, Aya Sadahiro, Alessandra Pontillo
Published 2020-10-01

Enhancement of CD4+ T Cell Function as a Strategy for Improving Antibiotic Therapy Efficacy in Tuberculosis: Does It Work?

by Diego L. Costa, Diego L. Costa, Diego L. Costa, Eduardo P. Amaral, Sivaranjani Namasivayam, Lara R. Mittereder, Lara R. Mittereder, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Alan Sher
Published 2021-06-01

Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis.

by Eduardo P Amaral, Simone C M Ribeiro, Verônica R Lanes, Fabrício M Almeida, Marcelle R M de Andrade, Caio Cesar Barbosa Bomfim, Erika M Salles, Karina R Bortoluci, Robson Coutinho-Silva, Mario H Hirata, José M Alvarez, Elena B Lasunskaia, Maria Regina D'Império-Lima
Published 2014-07-01

Hypervirulent Mycobacterium tuberculosis strain triggers necrotic lung pathology associated with enhanced recruitment of neutrophils in resistant C57BL/6 mice.

by Fabrício M Almeida, Thatiana L B Ventura, Eduardo P Amaral, Simone C M Ribeiro, Sanderson D Calixto, Marcelle R Manhães, Andreza L Rezende, Giliane S Souza, Igor S de Carvalho, Elisangela C Silva, Juliana Azevedo da Silva, Eulógio C Q Carvalho, Afranio L Kritski, Elena B Lasunskaia
Published 2017-01-01

Correction: Hypervirulent Mycobacterium tuberculosis strain triggers necrotic lung pathology associated with enhanced recruitment of neutrophils in resistant C57BL/6 mice.

by Fabrício M Almeida, Thatiana L B Ventura, Eduardo P Amaral, Simone C M Ribeiro, Sanderson D Calixto, Marcelle R Manhães, Andreza L Rezende, Giliane S Souza, Igor S de Carvalho, Elisangela C Silva, Juliana Azevedo da Silva, Eulógio C Q Carvalho, Afranio L Kritski, Elena B Lasunskaia
Published 2017-01-01

Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis

by Ivan P. Nascimento, Dunia Rodriguez, Carina C. Santos, Eduardo P. Amaral, Henrique K. Rofatto, Ana P. Junqueira-Kipnis, Eduardo D. C. Gonçalves, Maria R. D’Império-Lima, Mario H. Hirata, Celio L. Silva, Nathalie Winter, Brigitte Gicquel, Kingston H. G. Mills, Mariagrazia Pizza, Rino Rappuoli, Luciana C. C. Leite
Published 2017-05-01

Safety and efficacy of N-acetylcysteine in hospitalized patients with HIV-associated tuberculosis: An open-label, randomized, phase II trial (RIPENACTB Study).

by Izabella Picinin Safe, Marcus Vinícius Guimarães Lacerda, Vitoria Silva Printes, Adriana Ferreira Praia Marins, Amanda Lia Rebelo Rabelo, Amanda Araújo Costa, Michel Araújo Tavares, Jaquelane Silva Jesus, Alexandra Brito Souza, Francisco Beraldi-Magalhães, Cynthia Pessoa Neves, Wuelton Marcelo Monteiro, Vanderson Souza Sampaio, Eduardo P Amaral, Renata Spener Gomes, Bruno B Andrade, Marcelo Cordeiro-Santos
Published 2020-01-01

Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages

by Eduardo P. Amaral, Nicolas Riteau, Mahtab Moayeri, Nolan Maier, Katrin D. Mayer-Barber, Rosana M. Pereira, Silvia L. Lage, Andre Kubler, Andre Kubler, William R. Bishai, Maria R. D’Império-Lima, Alan Sher, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade
Published 2018-06-01

Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes

by Neesha Rockwood, Neesha Rockwood, Diego L. Costa, Eduardo P. Amaral, Elsa Du Bruyn, Andre Kubler, Andre Kubler, Leonardo Gil-Santana, Leonardo Gil-Santana, Leonardo Gil-Santana, Kiyoshi F. Fukutani, Charles A. Scanga, JoAnne L. Flynn, Sharon H. Jackson, Katalin A. Wilkinson, Katalin A. Wilkinson, William R. Bishai, Alan Sher, Robert J. Wilkinson, Robert J. Wilkinson, Robert J. Wilkinson, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade
Published 2017-05-01

Adjunct N-Acetylcysteine Treatment in Hospitalized Patients With HIV-Associated Tuberculosis Dampens the Oxidative Stress in Peripheral Blood: Results From the RIPENACTB Study Tria...

by Izabella P. Safe, Izabella P. Safe, Eduardo P. Amaral, Mariana Araújo-Pereira, Mariana Araújo-Pereira, Marcus V. G. Lacerda, Marcus V. G. Lacerda, Marcus V. G. Lacerda, Vitoria S. Printes, Vitoria S. Printes, Alexandra B. Souza, Francisco Beraldi-Magalhães, Wuelton M. Monteiro, Wuelton M. Monteiro, Vanderson S. Sampaio, Vanderson S. Sampaio, Beatriz Barreto-Duarte, Beatriz Barreto-Duarte, Beatriz Barreto-Duarte, Alice M. S. Andrade, Alice M. S. Andrade, Renata Spener-Gomes, Renata Spener-Gomes, Allyson Guimarães Costa, Allyson Guimarães Costa, Marcelo Cordeiro-Santos, Marcelo Cordeiro-Santos, Marcelo Cordeiro-Santos, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade
Published 2021-02-01