Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease.

by Sumit Punj, Prasad Kopparapu, Hyo Sang Jang, Jessica L Phillips, Jamie Pennington, Diana Rohlman, Edmond O'Donnell, Patrick L Iversen, Siva Kumar Kolluri, Nancy I Kerkvliet
Published 2014-01-01

503 Tumor infiltrating lymphocytes in soft tissue sarcomas upregulate the exhaustion marker TIGIT and are reinvigorated by IL-15 stimulation and TIGIT blockade

by Shuai Chen, Cordelia Dunai, Robert Rebhun, Arta Monjazeb, Ian Sturgill, Robert Canter, William Murphy, Yue Lyu, May Cho, Sean Judge, Morgan Darrow, Steven Thorpe, Alicia Gingrich, Edmond O’Donnell, Alyssa Bellini, Logan Vick, Kevin Stoffel
Published 2020-11-01