AHR Activation Is Protective against Colitis Driven by T Cells in Humanized Mice

by Jeremy A. Goettel, Roopali Gandhi, Jessica E. Kenison, Ada Yeste, Gopal Murugaiyan, Sharmila Sambanthamoorthy, Alexandra E. Griffith, Bonny Patel, Dror S. Shouval, Howard L. Weiner, Scott B. Snapper, Francisco J. Quintana
Published 2016-10-01

Alterations in T and B Cell Receptor Repertoires Patterns in Patients With IL10 Signaling Defects and History of Infantile-Onset IBD

by Lael Werner, Lael Werner, Yu Nee Lee, Yu Nee Lee, Yu Nee Lee, Yu Nee Lee, Erez Rechavi, Erez Rechavi, Erez Rechavi, Erez Rechavi, Atar Lev, Atar Lev, Atar Lev, Atar Lev, Baruch Yerushalmi, Galina Ling, Neil Shah, Holm H. Uhlig, Holm H. Uhlig, Holm H. Uhlig, Batia Weiss, Batia Weiss, Raz Somech, Raz Somech, Raz Somech, Raz Somech, Scott B. Snapper, Scott B. Snapper, Dror S. Shouval, Dror S. Shouval
Published 2020-02-01

In utero human intestine harbors unique metabolome, including bacterial metabolites

by Yujia Li, Jessica M. Toothaker, Shira Ben-Simon, Lital Ozeri, Ron Schweitzer, Blake T. McCourt, Collin C. McCourt, Lael Werner, Scott B. Snapper, Dror S. Shouval, Soliman Khatib, Omry Koren, Sameer Agnihorti, George Tseng, Liza Konnikova
Published 2020-11-01

Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis

by Iddo Vardi, Iddo Vardi, Iddo Vardi, Iddo Vardi, Irit Chermesh, Lael Werner, Lael Werner, Ortal Barel, Ortal Barel, Ortal Barel, Tal Freund, Tal Freund, Collin McCourt, Yael Fisher, Marina Pinsker, Marina Pinsker, Elisheva Javasky, Elisheva Javasky, Elisheva Javasky, Batia Weiss, Batia Weiss, Gideon Rechavi, Gideon Rechavi, Gideon Rechavi, David Hagin, David Hagin, Scott B. Snapper, Scott B. Snapper, Raz Somech, Raz Somech, Raz Somech, Raz Somech, Liza Konnikova, Liza Konnikova, Liza Konnikova, Dror S. Shouval, Dror S. Shouval
Published 2020-09-01

Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor

by Naresh S Redhu, Vasudevan Bakthavatchalu, Evan A Conaway, Dror S Shouval, Amy Tsou, Jeremy A Goettel, Amlan Biswas, Chuanwu Wang, Michael Field, Werner Muller, Andre Bleich, Ning Li, Georg K Gerber, Lynn Bry, James G Fox, Scott B Snapper, Bruce H Horwitz
Published 2017-07-01

WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis

by Amlan Biswas, Dror S. Shouval, Alexandra Griffith, Jeremy A. Goettel, Michael Field, Yu Hui Kang, Liza Konnikova, Erin Janssen, Naresh Singh Redhu, Adrian J. Thrasher, Talal Chatila, Vijay K. Kuchroo, Raif S Geha, Luigi D. Notarangelo, Sung-Yun Pai, Bruce H. Horwitz, Scott B. Snapper
Published 2018-05-01

Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer

by Oshrat Levi-Galibov, Hagar Lavon, Rina Wassermann-Dozorets, Meirav Pevsner-Fischer, Shimrit Mayer, Esther Wershof, Yaniv Stein, Lauren E. Brown, Wenhan Zhang, Gil Friedman, Reinat Nevo, Ofra Golani, Lior H. Katz, Rona Yaeger, Ido Laish, John A. Porco, Erik Sahai, Dror S. Shouval, David Kelsen, Ruth Scherz-Shouval
Published 2020-12-01

Enhanced Collagen Deposition in the Duodenum of Patients with Hyaline Fibromatosis Syndrome and Protein Losing Enteropathy

by Jorik M. van Rijn, Lael Werner, Yusuf Aydemir, Joey M.A. Spronck, Ben Pode-Shakked, Marliek van Hoesel, Elee Shimshoni, Sylvie Polak-Charcon, Liron Talmi, Makbule Eren, Batia Weiss, Roderick H.J. Houwen, Iris Barshack, Raz Somech, Edward E.S. Nieuwenhuis, Irit Sagi, Annick Raas-Rothschild, Sabine Middendorp, Dror S. Shouval
Published 2020-11-01