Dynamics of Internalization and Intracellular Interaction of Tau Antibodies and Human Pathological Tau Protein in a Human Neuron-Like Model

by Dov B. Shamir, Yan Deng, Qian Wu, Swananda Modak, Erin E. Congdon, Einar M. Sigurdsson, Einar M. Sigurdsson
Published 2020-11-01

Tau antibody chimerization alters its charge and binding, thereby reducing its cellular uptake and efficacyResearch in context

by Erin E. Congdon, Jessica E. Chukwu, Dov B. Shamir, Jingjing Deng, Devyani Ujla, Hameetha B.R. Sait, Thomas A. Neubert, Xiang-Peng Kong, Einar M. Sigurdsson
Published 2019-04-01