Biosynthesis of Polyunsaturated Fatty Acids in Marine Invertebrates: Recent Advances in Molecular Mechanisms

by Juan C. Navarro, Óscar Monroig, Douglas R. Tocher
Published 2013-10-01

Dietary Betaine Mitigates Hepatic Steatosis and Inflammation Induced by a High-Fat-Diet by Modulating the Sirt1/Srebp-1/Pparɑ Pathway in Juvenile Black Seabream (Acanthopagrus schl...

by Min Jin, Yuedong Shen, Tingting Pan, Tingting Zhu, Xuejiao Li, Fangmin Xu, Mónica B. Betancor, Lefei Jiao, Douglas R. Tocher, Douglas R. Tocher, Qicun Zhou
Published 2021-06-01

Omega-3 Long-Chain Polyunsaturated Fatty Acids, EPA and DHA: Bridging the Gap between Supply and Demand

by Douglas R Tocher, Monica B Betancor, Matthew Sprague, Rolf E Olsen, Johnathan A Napier
Published 2019-01-01

Influence of Development and Dietary Phospholipid Content and Composition on Intestinal Transcriptome of Atlantic Salmon (Salmo salar).

by Christian De Santis, John F Taylor, Laura Martinez-Rubio, Sebastian Boltana, Douglas R Tocher
Published 2015-01-01

Daily rhythms in expression of genes of hepatic lipid metabolism in Atlantic salmon (Salmo salar L.).

by Mónica B Betancor, Elsbeth McStay, Matteo Minghetti, Hervé Migaud, Douglas R Tocher, Andrew Davie
Published 2014-01-01

Temperature Increase Negatively Affects the Fatty Acid Bioconversion Capacity of Rainbow Trout (Oncorhynchus mykiss) Fed a Linseed Oil-Based Diet.

by Julie Mellery, Florian Geay, Douglas R Tocher, Patrick Kestemont, Cathy Debier, Xavier Rollin, Yvan Larondelle
Published 2016-01-01

Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates.

by Luís Filipe Costa Castro, Óscar Monroig, Michael J Leaver, Jonathan Wilson, Isabel Cunha, Douglas R Tocher
Published 2012-01-01

Cloning, functional characterization and nutritional regulation of Δ6 fatty acyl desaturase in the herbivorous euryhaline teleost Scatophagus argus.

by Dizhi Xie, Fang Chen, Siyuan Lin, Shuqi Wang, Cuihong You, Óscar Monroig, Douglas R Tocher, Yuanyou Li
Published 2014-01-01

Dietary DHA/EPA ratio affected tissue fatty acid profiles, antioxidant capacity, hematological characteristics and expression of lipid-related genes but not growth in juvenile blac...

by Min Jin, Óscar Monroig, You Lu, Ye Yuan, Yi Li, Liyun Ding, Douglas R Tocher, Qicun Zhou
Published 2017-01-01

Mass Production of Lemna minor and Its Amino Acid and Fatty Acid Profiles

by Rina Chakrabarti, William D. Clark, Jai Gopal Sharma, Ravi Kumar Goswami, Avanish Kumar Shrivastav, Douglas R. Tocher
Published 2018-10-01

Diversification of substrate specificities in teleostei Fads2: characterization of Δ4 and Δ6Δ5 desaturases of Chirostoma estor[S]

by Jorge Fonseca-Madrigal, Juan C. Navarro, Francisco Hontoria, Douglas R. Tocher, Carlos A. Martínez-Palacios, Óscar Monroig
Published 2014-07-01

Impact of Dietary Carbohydrate/Protein Ratio on Hepatic Metabolism in Land-Locked Atlantic Salmon (Salmo salar L.)

by Mónica B. Betancor, Rolf E. Olsen, Lucie Marandel, Ole F. Skulstad, Angelico Madaro, Douglas R. Tocher, Stephane Panserat
Published 2018-12-01

Isolation and Functional Characterisation of a fads2 in Rainbow Trout (Oncorhynchus mykiss) with Δ5 Desaturase Activity.

by Noor Khalidah Abdul Hamid, Greta Carmona-Antoñanzas, Óscar Monroig, Douglas R Tocher, Giovanni M Turchini, John A Donald
Published 2016-01-01

Two alternative pathways for docosahexaenoic acid (DHA, 22:6n-3) biosynthesis are widespread among teleost fish

by Angela Oboh, Naoki Kabeya, Greta Carmona-Antoñanzas, L. Filipe C. Castro, James R. Dick, Douglas R. Tocher, Oscar Monroig
Published 2017-06-01

Hepatocyte Nuclear Factor 4α (HNF4α) Is a Transcription Factor of Vertebrate Fatty Acyl Desaturase Gene as Identified in Marine Teleost Siganus canaliculatus.

by Yewei Dong, Shuqi Wang, Junliang Chen, Qinghao Zhang, Yang Liu, Cuihong You, Óscar Monroig, Douglas R Tocher, Yuanyou Li
Published 2016-01-01

Nutritional Evaluation of an EPA-DHA Oil from Transgenic Camelina sativa in Feeds for Post-Smolt Atlantic Salmon (Salmo salar L.).

by Mónica B Betancor, Matthew Sprague, Olga Sayanova, Sarah Usher, Christoforos Metochis, Patrick J Campbell, Johnathan A Napier, Douglas R Tocher
Published 2016-01-01

Functional feeds reduce heart inflammation and pathology in Atlantic Salmon (Salmo salar L.) following experimental challenge with Atlantic salmon reovirus (ASRV).

by Laura Martinez-Rubio, Sofia Morais, Øystein Evensen, Simon Wadsworth, Kari Ruohonen, Jose L G Vecino, J Gordon Bell, Douglas R Tocher
Published 2012-01-01

Sp1 is Involved in Vertebrate LC-PUFA Biosynthesis by Upregulating the Expression of Liver Desaturase and Elongase Genes

by Yuanyou Li, Jianhong Zhao, Yewei Dong, Ziyan Yin, Yang Li, Yang Liu, Cuihong You, Óscar Monroig, Douglas R. Tocher, Shuqi Wang
Published 2019-10-01

Retention of fatty acyl desaturase 1 (fads1) in Elopomorpha and Cyclostomata provides novel insights into the evolution of long-chain polyunsaturated fatty acid biosynthesis in ver...

by Mónica Lopes-Marques, Naoki Kabeya, Yu Qian, Raquel Ruivo, Miguel M. Santos, Byrappa Venkatesh, Douglas R. Tocher, L. Filipe C. Castro, Óscar Monroig
Published 2018-10-01

Dietary organic zinc promotes growth, immune response and antioxidant capacity by modulating zinc signaling in juvenile Pacific white shrimp (Litopenaeus vannamei)

by Bo Shi, Fangmin Xu, Qicun Zhou, Melanie K. Regan, Mónica B. Betancor, Douglas R. Tocher, Mihai Sun, Fanyi Meng, Lefei Jiao, Min Jin
Published 2021-03-01