Dendritic cells utilize the evolutionarily conserved WASH and retromer complexes to promote MHCII recycling and helper T cell priming.

by Daniel B Graham, Douglas G Osborne, Joshua T Piotrowski, Timothy S Gomez, Grzegorz B Gmyrek, Holly M Akilesh, Adish Dani, Daniel D Billadeau, Wojciech Swat
Published 2014-01-01

Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation

by Glenn F.W. Walpole, Jonathan D. Plumb, Daniel Chung, Brandon Tang, Benoit Boulay, Douglas G. Osborne, Joshua T. Piotrowski, Sergio D. Catz, Daniel D. Billadeau, Sergio Grinstein, Valentin Jaumouillé
Published 2020-06-01

Structural and mechanistic insights into regulation of the retromer coat by TBC1d5

by Da Jia, Jin-San Zhang, Fang Li, Jing Wang, Zhihui Deng, Mark A. White, Douglas G. Osborne, Christine Phillips-Krawczak, Timothy S. Gomez, Haiying Li, Amika Singla, Ezra Burstein, Daniel D. Billadeau, Michael K. Rosen
Published 2016-11-01

Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis

by Eric T Clambey, Jacob Gadwa, Thomas E Bickett, Laurel B Darragh, Shilpa Bhatia, Miles Piper, Benjamin Van Court, Shiv Bhuvane, Diemmy Nguyen, Varuna Nangia, Sana D Karam, Michael W Knitz, Ayman J Oweida, Adam C Mueller, Douglas G Osborne, Xiyuan Bai, Sarah E Ferrara, Mary-Keara Boss, Andrew Goodspeed, Matthew A Burchill, Beth A Jirón Tamburini, Edward D Chan, Curtis R Pickering
Published 2021-04-01