In Vitro-In Vivo Translation of Lipid Nanoparticles for Hepatocellular siRNA Delivery

by Matthews, Jonathan, Chang, Philip H., Niroui, Farnaz, Severgnini, Mariano, Whitehead, Kathryn Ann, Dorkin, Joseph Robert, Anderson, Daniel Griffith
Published 2014

Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy

by Oberli, Matthias, Reichmuth, Andreas Michael, Dorkin, Joseph Robert, Mitchell, Michael J, Jaklenec, Ana, Anderson, Daniel Griffith, Langer, Robert S, Fenton, Owen Shea, Blankschtein, Daniel
Published 2018

Poly(glycoamidoamine) brush nanomaterials for systemic siRNA delivery in vivo

by Luo, X., Wang, Wei, Dorkin, Joseph Robert, Veiseh, Omid, Chang, Pyung-Hun, Abutbul-Ionita, I., Danino, D., Langer, Robert S, Anderson, Daniel Griffith, Dong, Y.
Published 2019

Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse

by Kauffman, Kevin John, Oberli, Matthias, Dorkin, Joseph Robert, Hurtado, Juan E., Kaczmarek, James Cliff, Bhadani, Shivani, Wyckoff, Jeffrey, Langer, Robert S, Jaklenec, Ana, Anderson, Daniel Griffith
Published 2019

Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system

by DeRosa, F, Guild, B, Karve, S, Smith, L, Zhang, J, Yahalom, B, Heartlein, M W, Love, Kerry R., Dorkin, Joseph Robert, Kauffman, Kevin John, Anderson, Daniel Griffith
Published 2017

Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery

by DeRosa, Frank, Langer, Robert, Kauffman, Kevin John, McClellan, Rebecca L, Appel, Eric, Dorkin, Joseph Robert, Tibbitt, Mark W, Langer, Robert S, Anderson, Daniel Griffith, Fenton, Owen Shea
Published 2017

Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo

by Abutbul-Ionita, Inbal, Danino, Dganit, DeRosa, Frank, Heartlein, Michael, Dong, Yizhou, Dorkin, Joseph Robert, Wang, Weiheng, Webber, Matthew, Tang, Benjamin C., Yang, Jung H, Langer, Robert S, Anderson, Daniel Griffith, Chang, Philip H.
Published 2017

Lipid-Like Nanomaterials for Simultaneous Gene Expression and Silencing In Vivo

by Dong, Yizhou, Eltoukhy, Ahmed A., Alabi, Christopher A., Veiseh, Omid, Sirirungruang, Sasilada, Yin, Hao, Tang, Benjamin C., Chen, Delai, Gu, Zhen, Xue, Yuan, Anderson, Daniel Griffith, Pelet, Jeisa, Langer, Robert S, Khan, Omar Fizal, Dorkin, Joseph Robert
Published 2016

Lipid-like materials for low-dose, in vivo gene silencing

by Mahon, Kerry P., Levins, Christopher G., Whitehead, Kathryn Ann, Querbes, William, Dorkin, Joseph Robert, Qin, June, Cantley, William, Qin, Liu Liang, Racie, Timothy, Frank-Kamenetsky, Maria, Yip, Ka, Alvarez, Rene, Sah, Dinah W. Y., de Fougerolles, Antonin, Fitzgerald, Kevin, Kotelianski, Victor E., Akinc, Akin, Love, Kevin T, Langer, Robert S, Anderson, Daniel Griffith
Published 2011

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

by Dong, Yizhou, Love, Kevin T., Dorkin, Joseph Robert, Sirirungruang, Sasilada, Zhang, Yunlong, Chen, Delai, Bogorad, Roman, Yin, Hao, Chen, Yi, Vegas, Arturo, Alabi, Christopher A., Sahay, Gaurav, Olejnik, Karsten, Wang, Weiheng, Schroeder, Avi, Lytton-Jean, Abigail K. R., Siegwart, Daniel J., Akinc, Akin, Barnes, Carmen, Barros, Scott A., Carioto, Mary, Fitzgerald, Kevin, Hettinger, Julia, Kumar, Varun, Novobrantseva, Tatiana I., Qin, June, Querbes, William, Kotelianski, Victor E., Langer, Robert, Anderson, Daniel Griffith
Published 2014