IP6 Regulation of HIV Capsid Assembly, Stability, and Uncoating

by Robert A. Dick, Donna L. Mallery, Volker M. Vogt, Leo C. James
Published 2018-11-01

BRCA1 Is a Histone-H2A-Specific Ubiquitin Ligase

by Reinhard Kalb, Donna L. Mallery, Conor Larkin, Jeffrey T.J. Huang, Kevin Hiom
Published 2014-08-01

A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly.

by Nadine Renner, Donna L Mallery, K M Rifat Faysal, Wang Peng, David A Jacques, Till Böcking, Leo C James
Published 2021-02-01

A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases

by Leo Kiss, Jingwei Zeng, Claire F. Dickson, Donna L. Mallery, Ji-Chun Yang, Stephen H. McLaughlin, Andreas Boland, David Neuhaus, Leo C. James
Published 2019-10-01

IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis

by Donna L Mallery, Chantal L Márquez, William A McEwan, Claire F Dickson, David A Jacques, Madhanagopal Anandapadamanaban, Katsiaryna Bichel, Gregory J Towers, Adolfo Saiardi, Till Böcking, Leo C James
Published 2018-05-01

Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion.

by Guido Papa, Donna L Mallery, Anna Albecka, Lawrence G Welch, Jérôme Cattin-Ortolá, Jakub Luptak, David Paul, Harvey T McMahon, Ian G Goodfellow, Andrew Carter, Sean Munro, Leo C James
Published 2021-01-01

Cellular IP6 Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP6 Are Attenuated for Infection and Replication

by Donna L. Mallery, K.M. Rifat Faysal, Alex Kleinpeter, Miranda S.C. Wilson, Marina Vaysburd, Adam J. Fletcher, Mariia Novikova, Till Böcking, Eric O. Freed, Adolfo Saiardi, Leo C. James
Published 2019-12-01

Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21

by Claire Dickson, Adam J Fletcher, Marina Vaysburd, Ji-Chun Yang, Donna L Mallery, Jingwei Zeng, Christopher M Johnson, Stephen H McLaughlin, Mark Skehel, Sarah Maslen, James Cruickshank, Nicolas Huguenin-Dezot, Jason W Chin, David Neuhaus, Leo C James
Published 2018-04-01