Inhibition of PFKFB3 Hampers the Progression of Atherosclerosis and Promotes Plaque Stability

by Kikkie Poels, Johan G. Schnitzler, Farahnaz Waissi, Farahnaz Waissi, Farahnaz Waissi, Johannes H. M. Levels, Erik S. G. Stroes, Mat J. A. P. Daemen, Esther Lutgens, Esther Lutgens, Esther Lutgens, Anne-Marije Pennekamp, Dominique P. V. De Kleijn, Dominique P. V. De Kleijn, Dominique P. V. De Kleijn, Tom T. P. Seijkens, Jeffrey Kroon
Published 2020-11-01

Extracellular Vesicles in Diagnosing Chronic Coronary Syndromes—The Bumpy Road to Clinical Implementation

by Mirthe Dekker, Farahnaz Waissi, Nathalie Timmerman, Max J. M. Silvis, Leo Timmers, Dominique P. V. de Kleijn
Published 2020-11-01

Extracellular Vesicle cystatin c is associated with unstable angina in troponin negative patients with acute chest pain.

by Mirthe Dekker, Farahnaz Waissi, Joelle van Bennekom, Max J M Silvis, Nathalie Timmerman, Arjan H Schoneveld, Diederick E Grobbee, Robbert J de Winter, Arend Mosterd, Leo Timmers, Dominique P V de Kleijn
Published 2020-01-01

Automated calcium scores collected during myocardial perfusion imaging improve identification of obstructive coronary artery disease

by Mirthe Dekker, Farahnaz Waissi, Ingrid E.M. Bank, Nikolas Lessmann, Ivana Išgum, Birgitta K. Velthuis, Asbjørn M. Scholtens, Geert E. Leenders, Gerard Pasterkamp, Dominique P.V. de Kleijn, Leo Timmers, Arend Mosterd
Published 2020-02-01

Experimental parameters and infarct size in closed chest pig LAD ischemia reperfusion models; lessons learned

by Max J. M. Silvis, Gerardus P. J. van Hout, Aernoud T. L. Fiolet, Mirthe Dekker, Lena Bosch, Martijn M. J. van Nieuwburg, Joyce Visser, Marlijn S. Jansen, Leo Timmers, Dominique P. V. de Kleijn
Published 2021-04-01

Co-prevalence of extracranial carotid aneurysms differs between European intracranial aneurysm cohorts.

by Constance J H C M van Laarhoven, Vanessa E C Pourier, Antti E Lindgren, Mervyn D I Vergouwen, Juha E Jääskeläinen, Gabriël J E Rinkel, Dominique P V de Kleijn, Gert J de Borst
Published 2020-01-01

Sex differences in flow cytometry–based platelet reactivity in stable outpatients suspected of myocardial ischemia

by Farahnaz Waissi, Mirthe Dekker, Ingrid E.M. Bank, Suzanne J.A. Korporaal, Rolf T. Urbanus, Gert J. deBorst, Gerard Pasterkamp, Asbjorn M. Scholtens, Diederick E. Grobbee, Arend Mosterd, Dominique P.V. deKleijn, Leo Timmers
Published 2020-07-01

Lowering Low-Density Lipoprotein Particles in Plasma Using Dextran Sulphate Co-Precipitates Procoagulant Extracellular Vesicles

by Jiong-Wei Wang, Ya-Nan Zhang, Siu Kwan Sze, Sander M. van de Weg, Flora Vernooij, Arjan H. Schoneveld, Sock-Hwee Tan, Henri H. Versteeg, Leo Timmers, Carolyn S. P. Lam, Dominique P. V. de Kleijn
Published 2017-12-01

Inter-Ethnic Differences in Quantified Coronary Artery Disease Severity and All-Cause Mortality among Dutch and Singaporean Percutaneous Coronary Intervention Patients.

by Crystel M Gijsberts, Aruni Seneviratna, Imo E Hoefer, Pierfrancesco Agostoni, Saskia Z H Rittersma, Gerard Pasterkamp, Mikael Hartman, Leonardo Pinto de Carvalho, A Mark Richards, Folkert W Asselbergs, Dominique P V de Kleijn, Mark Y Chan
Published 2015-01-01

High levels of osteoprotegerin are associated with coronary artery calcification in patients suspected of a chronic coronary syndrome

by Mirthe Dekker, Farahnaz Waissi, Max J. M. Silvis, Joelle V. Bennekom, Arjan H. Schoneveld, Robbert J. de Winter, Ivana Isgum, Nikolas Lessmann, Birgitta K. Velthuis, Gerard Pasterkamp, Arend Mosterd, Leo Timmers, Dominique P. V. de Kleijn
Published 2021-09-01

A porcine model of heart failure with preserved ejection fraction: magnetic resonance imaging and metabolic energetics

by Christopher J. Charles, Philip Lee, Renee R. Li, Teresa Yeung, Stephane M. Ibraham Mazlan, Zhi Wei Tay, Desiree Abdurrachim, Xing Qi Teo, Wei‐Hsin Wang, Dominique P.V. deKleijn, Patrick J. Cozzone, Carolyn S.P. Lam, A. Mark Richards
Published 2020-02-01

Caveolin-1 influences vascular protease activity and is a potential stabilizing factor in human atherosclerotic disease.

by Juan A Rodriguez-Feo, Willem E Hellings, Frans L Moll, Jean-Paul P M De Vries, Ben J van Middelaar, Ale Algra, Joost Sluijter, Evelyn Velema, Theo van den Broek, William C Sessa, Dominique P V De Kleijn, Gerard Pasterkamp
Published 2008-01-01

Extracellular vesicle Cystatin C and CD14 are associated with both renal dysfunction and heart failure

by Laura Verbree‐Willemsen, Ya‐nan Zhang, Irwani Ibrahim, Shirley B.S. Ooi, Jiong‐Wei Wang, Muhammad I. Mazlan, Win S. Kuan, Siew‐Pang Chan, Linda M. Peelen, Diederick E. Grobbee, A. Mark Richards, Carolyn S.P. Lam, Dominique P.V. deKleijn
Published 2020-10-01

Leukocytic Toll-Like Receptor 2 Deficiency Preserves Cardiac Function And Reduces Fibrosis In Sustained Pressure Overload

by Jiong-Wei Wang, Magda S. C. Fontes, Xiaoyuan Wang, Suet Yen Chong, Elise L. Kessler, Ya-Nan Zhang, Judith J. de Haan, Fatih Arslan, Saskia C. A. de Jager, Leo Timmers, Toon A. B. van Veen, Carolyn S. P. Lam, Dominique P. V. de Kleijn
Published 2017-08-01

In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors

by Lynn Yap, Jiong-Wei Wang, Aida Moreno-Moral, Li Yen Chong, Yi Sun, Nathan Harmston, Xiaoyuan Wang, Suet Yen Chong, Miina K. Öhman, Heming Wei, Ralph Bunte, Sujoy Gosh, Stuart Cook, Outi Hovatta, Dominique P.V. de Kleijn, Enrico Petretto, Karl Tryggvason
Published 2019-03-01

Extracellular Vesicle Proteins Associated with Systemic Vascular Events Correlate with Heart Failure: An Observational Study in a Dyspnoea Cohort.

by Ya-Nan Zhang, Flora Vernooij, Irwani Ibrahim, Shirley Ooi, Crystel M Gijsberts, Arjan H Schoneveld, Kuan Win Sen, Hester M den Ruijter, Leo Timmers, Arthur Mark Richards, Chun Tzen Jong, Ibrahim Mazlan, Jiong-Wei Wang, Carolyn S P Lam, Dominique P V de Kleijn
Published 2016-01-01

In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors

by Lynn Yap, Jiong-Wei Wang, Aida Moreno-Moral, Li Yen Chong, Yi Sun, Nathan Harmston, Xiaoyuan Wang, Suet Yen Chong, Konstantinos Vanezis, Miina K. Öhman, Heming Wei, Ralph Bunte, Sujoy Gosh, Stuart Cook, Outi Hovatta, Dominique P.V. de Kleijn, Enrico Petretto, Karl Tryggvason
Published 2020-05-01

Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis.

by Sanne Willems, Daniël van der Velden, Paul H A Quax, Gert Jan de Borst, Jean-Paul P M de Vries, Frans L Moll, Johan Kuiper, René E M Toes, Saskia C A de Jager, Dominique P V de Kleijn, Imo E Hoefer, Gerard Pasterkamp, Ilze Bot
Published 2014-01-01

Systemic Mesenchymal Stem Cell-Derived Exosomes Reduce Myocardial Infarct Size: Characterization With MRI in a Porcine Model

by Christopher J. Charles, Christopher J. Charles, Christopher J. Charles, Renee R. Li, Renee R. Li, Teresa Yeung, Teresa Yeung, Stephane M. Ibraham Mazlan, Stephane M. Ibraham Mazlan, Ruenn Chai Lai, Dominique P. V. de Kleijn, Sai Kiang Lim, Sai Kiang Lim, A. Mark Richards, A. Mark Richards
Published 2020-11-01

Plasma extracellular vesicle proteins are associated with stress-induced myocardial ischemia in women presenting with chest pain

by Mirthe Dekker, Farahnaz Waissi, Joelle van Bennekom, Max J. M. Silvis, Nathalie Timmerman, Ingrid E. M. Bank, Joan E. Walter, Christian Mueller, A. H. Schoneveld, Raymond M. Schiffelers, Gerard Pasterkamp, Diederick E. Grobbee, Robbert J. de Winter, A. Mosterd, Dominique P. V. de Kleijn, Leo Timmers
Published 2020-07-01