Transcriptome analysis revealed unique genes as targets for the anti-inflammatory action of activated protein C in human macrophages.

by Claudia P Pereira, Esther B Bachli, Dominik J Schaer, Gabriele Schoedon
Published 2010-01-01

Human Plasma and Recombinant Hemopexins: Heme Binding Revisited

by Elena Karnaukhova, Catherine Owczarek, Peter Schmidt, Dominik J. Schaer, Paul W. Buehler
Published 2021-01-01

Chloroquine Interference with Hemoglobin Endocytic Trafficking Suppresses Adaptive Heme and Iron Homeostasis in Macrophages: The Paradox of an Antimalarial Agent

by Christian A. Schaer, Endre Laczko, Gabriele Schoedon, Dominik J. Schaer, Florence Vallelian
Published 2013-01-01

Modelling hemoglobin and hemoglobin:haptoglobin complex clearance in a non-rodent species– pharmacokinetic and therapeutic implications

by Felicitas S Boretti, Jin H Baek, Andre F Palmer, Dominik J Schaer, Paul W Buehler
Published 2014-10-01

Haptoglobin, hemopexin and related defense pathways—basic science, clinical perspectives and drug development

by Dominik J Schaer, Francesca eVinchi, Giada eIngoglia, Emanuela eTolosano, Paul eBuehler
Published 2014-10-01

Haptoglobin treatment prevents cell-free hemoglobin exacerbated mortality in experimental rat sepsis

by Christian A. Schaer, Victor Jeger, Thomas Gentinetta, Donat R. Spahn, Florence Vallelian, Alain Rudiger, Dominik J. Schaer
Published 2021-05-01

Extracellular Hb Enhances Cardiac Toxicity in Endotoxemic Guinea Pigs: Protective Role of Haptoglobin

by Jin Hyen Baek, Xiaoyuan Zhang, Matthew C. Williams, Dominik J. Schaer, Paul W. Buehler, Felice D'Agnillo
Published 2014-03-01

Acute Hemolysis and Heme Suppress Anti-CD40 Antibody-Induced Necro-Inflammatory Liver Disease

by Marc Pfefferlé, Giada Ingoglia, Christian A. Schaer, Kerstin Hansen, Nadja Schulthess, Rok Humar, Dominik J. Schaer, Florence Vallelian
Published 2021-05-01

Agonistic Anti-CD40 Antibody Triggers an Acute Liver Crisis With Systemic Inflammation in Humanized Sickle Cell Disease Mice

by Ayla Yalamanoglu, Irina L. Dubach, Nadja Schulthess, Giada Ingoglia, Delaney C. Swindle, Rok Humar, Dominik J. Schaer, Paul W. Buehler, Paul W. Buehler, David C. Irwin, Florence Vallelian
Published 2021-03-01

Phenotype-specific recombinant haptoglobin polymers co-expressed with C1r-like protein as optimized hemoglobin-binding therapeutics

by Christian A. Schaer, Catherine Owczarek, Jeremy W. Deuel, Stefan Schauer, Jin Hyen Baek, Ayla Yalamanoglu, Matthew P. Hardy, Pierre D. Scotney, Peter M. Schmidt, Matthias Pelzing, Peter Soupourmas, Paul W. Buehler, Dominik J. Schaer
Published 2018-03-01

Clonal Hematopoiesis in Hospitalized Elderly Patients With COVID-19

by Erik Hameister, Sebastian M. Stolz, Yvonne Fuhrer, Friedrich Thienemann, Dominik J. Schaer, Johannes Nemeth, Reto A. Schuepbach, Jeroen Goede, Sophie Reinhart, Adrian Schmidt, Abdullah Kahraman, Mathias Schmid, Holger Moch, Martin Zoche, Markus G. Manz, Stefan Balabanov, Steffen Boettcher
Published 2020-08-01