Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS

by Byrne, K., Calvo, S.E, Doench, J.G, Goldberger, O., Mootha, V.K, Reinstadler, B., Shah, H., Shen, H., Shi, X., Summer, L., To, T.-L
Published 2022

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

by Hartenian, E., Shi, X., Mikkelsen, T. S., Heckl, D., Ebert, B. L., Root, D. E., Doench, J. G., Shalem, Ophir, Sanjana, Neville E, Scott, David Arthur, Zhang, Feng
Published 2017

PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment

by Al Abosy, R., Bi, K., Boehm, J.S, Collins, N.B, Doench, J.G, Hahn, W.C, Haining, W.N, Hughes, T., Ishizuka, J.J, Manguso, R.T, Miller, B.C, Pope, H.W, Quigley, M., Shalek, A.K, Shrestha, Y., Wadsworth, M., Yates, K.B, Zhao, Q.
Published 2022