Base Sequence Context Effects on Nucleotide Excision Repair

by Yuqin Cai, Dinshaw J. Patel, Suse Broyde, Nicholas E. Geacintov
Published 2010-01-01

Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX

by Dominik Hoelper, Hongda Huang, Aayushi Y. Jain, Dinshaw J. Patel, Peter W. Lewis
Published 2017-10-01

Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch

by Aiming Ren, Yi Xue, Alla Peselis, Alexander Serganov, Hashim M. Al-Hashimi, Dinshaw J. Patel
Published 2015-12-01

Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.

by Olga Rechkoblit, Lucy Malinina, Yuan Cheng, Vitaly Kuryavyi, Suse Broyde, Nicholas E Geacintov, Dinshaw J Patel
Published 2006-01-01

Structural basis underlying viral hijacking of a histone chaperone complex

by Hongda Huang, Zhong Deng, Olga Vladimirova, Andreas Wiedmer, Fang Lu, Paul M. Lieberman, Dinshaw J. Patel
Published 2016-09-01

Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA

by Yiwei Liu, Daria Esyunina, Ivan Olovnikov, Marianna Teplova, Andrey Kulbachinskiy, Alexei A. Aravin, Dinshaw J. Patel
Published 2018-07-01

The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure.

by Lucy Malinina, Margarita L Malakhova, Alex T Kanack, Min Lu, Ruben Abagyan, Rhoderick E Brown, Dinshaw J Patel
Published 2006-11-01

Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme

by Luqian Zheng, Elisabeth Mairhofer, Marianna Teplova, Ye Zhang, Jinbiao Ma, Dinshaw J. Patel, Ronald Micura, Aiming Ren
Published 2017-10-01

Structural Basis for Molecular Discrimination by a 3′,3′-cGAMP Sensing Riboswitch

by Aiming Ren, Xin C. Wang, Colleen A. Kellenberger, Kanagalaghatta R. Rajashankar, Roger A. Jones, Ming C. Hammond, Dinshaw J. Patel
Published 2015-04-01

Structural Basis for Molecular Discrimination by a 3′,3′-cGAMP Sensing Riboswitch

by Aiming Ren, Xin C. Wang, Colleen A. Kellenberger, Kanagalaghatta R. Rajashankar, Roger A. Jones, Ming C. Hammond, Dinshaw J. Patel
Published 2015-04-01

Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA

by Pu Gao, Thomas Zillinger, Weiyi Wang, Manuel Ascano, Peihong Dai, Gunther Hartmann, Thomas Tuschl, Liang Deng, Winfried Barchet, Dinshaw J. Patel
Published 2014-09-01

Eukaryote-Specific Insertion Elements Control Human ARGONAUTE Slicer Activity

by Kotaro Nakanishi, Manuel Ascano, Tasos Gogakos, Satoko Ishibe-Murakami, Artem A. Serganov, Daniel Briskin, Pavel Morozov, Thomas Tuschl, Dinshaw J. Patel
Published 2013-06-01

Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex

by Xiawei Huang, Hongmiao Hu, Alexandre Webster, Fan Zou, Jiamu Du, Dinshaw J. Patel, Ravi Sachidanandam, Katalin Fejes Toth, Alexei A. Aravin, Sisi Li
Published 2021-07-01

Structural basis of phosphatidylcholine recognition by the C2–domain of cytosolic phospholipase A2α

by Yoshinori Hirano, Yong-Guang Gao, Daniel J Stephenson, Ngoc T Vu, Lucy Malinina, Dhirendra K Simanshu, Charles E Chalfant, Dinshaw J Patel, Rhoderick E Brown
Published 2019-05-01

Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis.

by Marcel Hohl, Aditya Mojumdar, Sarem Hailemariam, Vitaly Kuryavyi, Fiorella Ghisays, Kyle Sorenson, Matthew Chang, Barry S Taylor, Dinshaw J Patel, Peter M Burgers, Jennifer A Cobb, John H J Petrini
Published 2020-03-01

Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels

by Dhirendra K. Simanshu, Xiuhong Zhai, David Munch, Daniel Hofius, Jonathan E. Markham, Jacek Bielawski, Alicja Bielawska, Lucy Malinina, Julian G. Molotkovsky, John W. Mundy, Dinshaw J. Patel, Rhoderick E. Brown
Published 2014-01-01

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

by Jessica Vincent, Carolina Adura, Pu Gao, Antonio Luz, Lodoe Lama, Yasutomi Asano, Rei Okamoto, Toshihiro Imaeda, Jumpei Aida, Katherine Rothamel, Tasos Gogakos, Joshua Steinberg, Seth Reasoner, Kazuyoshi Aso, Thomas Tuschl, Dinshaw J. Patel, J. Fraser Glickman, Manuel Ascano
Published 2017-09-01

Publisher Correction: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

by Jessica Vincent, Carolina Adura, Pu Gao, Antonio Luz, Lodoe Lama, Yasutomi Asano, Rei Okamoto, Toshihiro Imaeda, Jumpei Aida, Katherine Rothamel, Tasos Gogakos, Joshua Steinberg, Seth Reasoner, Kazuyoshi Aso, Thomas Tuschl, Dinshaw J. Patel, J. Fraser Glickman, Manuel Ascano
Published 2017-11-01

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

by Lodoe Lama, Carolina Adura, Wei Xie, Daisuke Tomita, Taku Kamei, Vitaly Kuryavyi, Tasos Gogakos, Joshua I. Steinberg, Michael Miller, Lavoisier Ramos-Espiritu, Yasutomi Asano, Shogo Hashizume, Jumpei Aida, Toshihiro Imaeda, Rei Okamoto, Andy J. Jennings, Mayako Michino, Takanobu Kuroita, Andrew Stamford, Pu Gao, Peter Meinke, J. Fraser Glickman, Dinshaw J. Patel, Thomas Tuschl
Published 2019-05-01

DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation

by Wendan Ren, Huitao Fan, Sara A. Grimm, Jae Jin Kim, Linhui Li, Yiran Guo, Christopher James Petell, Xiao-Feng Tan, Zhi-Min Zhang, John P. Coan, Jiekai Yin, Dae In Kim, Linfeng Gao, Ling Cai, Nelli Khudaverdyan, Burak Çetin, Dinshaw J. Patel, Yinsheng Wang, Qiang Cui, Brian D. Strahl, Or Gozani, Kyle M. Miller, Seán E. O’Leary, Paul A. Wade, Gang Greg Wang, Jikui Song
Published 2021-05-01