Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses

by Tytti Heinonen, Eleonora Ciarlo, Didier Le Roy, Thierry Roger
Published 2019-10-01

Mouse Model of Respiratory Tract Infection Induced by Waddlia chondrophila.

by Ludovic Pilloux, Didier LeRoy, Christophe Brunel, Thierry Roger, Gilbert Greub
Published 2016-01-01

Dual Deletion of the Sirtuins SIRT2 and SIRT3 Impacts on Metabolism and Inflammatory Responses of Macrophages and Protects From Endotoxemia

by Tytti Heinonen, Eleonora Ciarlo, Ersilia Rigoni, Jean Regina, Didier Le Roy, Thierry Roger
Published 2019-11-01

Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections

by Tytti Heinonen, Eleonora Ciarlo, Charlotte Théroude, Aimilia Pelekanou, Jacobus Herderschee, Didier Le Roy, Thierry Roger
Published 2018-11-01

Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections

by Eleonora Ciarlo, Tytti Heinonen, Jérôme Lugrin, Hans Acha-Orbea, Didier Le Roy, Johan Auwerx, Thierry Roger
Published 2017-06-01

The Anticancer Peptide TAT-RasGAP317−326 Exerts Broad Antimicrobial Activity

by Mathieu Heulot, Nicolas Jacquier, Sébastien Aeby, Didier Le Roy, Thierry Roger, Evgeniya Trofimenko, David Barras, Gilbert Greub, Christian Widmann
Published 2017-06-01

Trained Immunity Confers Prolonged Protection From Listeriosis

by Charlotte Théroude, Marta Reverte, Tytti Heinonen, Eleonora Ciarlo, Irene T. Schrijver, Nikolaos Antonakos, Nicolas Maillard, Florian Pralong, Didier Le Roy, Thierry Roger
Published 2021-09-01

Sirtuin 2 Deficiency Increases Bacterial Phagocytosis by Macrophages and Protects from Chronic Staphylococcal Infection

by Eleonora Ciarlo, Tytti Heinonen, Charlotte Théroude, Jacobus Herderschee, Matteo Mombelli, Jérôme Lugrin, Marc Pfefferlé, Beatrice Tyrrell, Sarah Lensch, Hans Acha-Orbea, Didier Le Roy, Johan Auwerx, Thierry Roger
Published 2017-08-01

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.

by Julie Delaloye, Thierry Roger, Quynh-Giao Steiner-Tardivel, Didier Le Roy, Marlies Knaup Reymond, Shizuo Akira, Virginie Petrilli, Carmen E Gomez, Beatriz Perdiguero, Jürg Tschopp, Giuseppe Pantaleo, Mariano Esteban, Thierry Calandra
Published 2009-06-01

Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis.

by W Joost Wiersinga, Thierry Calandra, Liesbeth M Kager, Gerritje J W van der Windt, Thierry Roger, Didier le Roy, Sandrine Florquin, Sharon J Peacock, Fred C G J Sweep, Tom van der Poll
Published 2010-02-01