Cell-Based Therapy Manufacturing in Stirred Suspension Bioreactor: Thoughts for cGMP Compliance

by Suman C. Nath, Suman C. Nath, Lane Harper, Derrick E. Rancourt, Derrick E. Rancourt
Published 2020-11-01

Identification of five developmental processes during chondrogenic differentiation of embryonic stem cells.

by Akihiro Yamashita, Sandi Nishikawa, Derrick E Rancourt
Published 2010-06-01

Microenvironment modulates osteogenic cell lineage commitment in differentiated embryonic stem cells.

by Akihiro Yamashita, Sandi Nishikawa, Derrick E Rancourt
Published 2010-03-01

Cytokine Directed Chondroblast Trans-Differentiation: <i>JAK</i> Inhibition Facilitates Direct Reprogramming of Fibroblasts to Chondroblasts

by Perla Cota, Summer A. Helmi, Charlie Hsu, Derrick E. Rancourt
Published 2020-01-01

Going (Reo)Viral: Factors Promoting Successful Reoviral Oncolytic Infection

by Tarryn Bourhill, Yoshinori Mori, Derrick E. Rancourt, Maya Shmulevitz, Randal N. Johnston
Published 2018-08-01

Inhibition of Rho kinase regulates specification of early differentiation events in P19 embryonal carcinoma stem cells.

by Roman J Krawetz, Jaymi Taiani, Alexis Greene, Gregory M Kelly, Derrick E Rancourt
Published 2011-01-01

An Integrated Approach toward the Biomanufacturing of Engineered Cell Therapy Products in a Stirred-Suspension Bioreactor

by Charlie Y.M. Hsu, Tylor Walsh, Breanna S. Borys, Michael S. Kallos, Derrick E. Rancourt
Published 2018-06-01

Enhanced Osteogenic Differentiation of Pluripotent Stem Cells via γ-Secretase Inhibition

by Summer A. Helmi, Leili Rohani, Ahmed R. Zaher, Youssry M. El Hawary, Derrick E. Rancourt
Published 2021-05-01

Post-Passage rock inhibition induces cytoskeletal aberrations and apoptosis in Human embryonic stem cells

by Lijie Gao, Suman C. Nath, Xiyao Jiao, Rongyan Zhou, Sandra Nishikawa, Roman Krawetz, Xiangyun Li, Derrick E. Rancourt
Published 2019-12-01

Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors.

by Navneet Sharma, Rajeev Kumar, Bernard Renaux, Mahmoud Saifeddine, Sandra Nishikawa, Koichiro Mihara, Rithwik Ramachandran, Morley D Hollenberg, Derrick E Rancourt
Published 2011-01-01

Embryonic Stem Cells Incorporate into Newly Formed Bone and do Not Form Tumors in an Immunocompetent Mouse Fracture Model

by Jaymi T. Taiani, Roman J. Krawetz, Akihiro Yamashita, Yves Pauchard, Helen R. Buie, Dragana Ponjevic, Steven K. Boyd, Derrick E. Rancourt, John R. Matyas
Published 2013-08-01

Overcoming bioprocess bottlenecks in the large-scale expansion of high-quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors

by Breanna S. Borys, Tiffany Dang, Tania So, Leili Rohani, Tamas Revay, Tylor Walsh, Madalynn Thompson, Bob Argiropoulos, Derrick E. Rancourt, Sunghoon Jung, Yas Hashimura, Brian Lee, Michael S. Kallos
Published 2021-01-01

Optimized serial expansion of human induced pluripotent stem cells using low‐density inoculation to generate clinically relevant quantities in vertical‐wheel bioreactors

by Breanna S. Borys, Tania So, James Colter, Tiffany Dang, Erin L. Roberts, Tamas Revay, Leila Larijani, Roman Krawetz, Ian Lewis, Bob Argiropoulos, Derrick E. Rancourt, Sunghoon Jung, Yas Hashimura, Brian Lee, Michael S. Kallos
Published 2020-09-01