Obesity, Type 2 Diabetes, and Cancer Risk

by Tiffany Scully, Abora Ettela, Derek LeRoith, Derek LeRoith, Emily Jane Gallagher, Emily Jane Gallagher
Published 2021-02-01

Editorial: What's New in Endocrinology?

by Jeff M. P. Holly, Derek LeRoith
Published 2019-12-01

A Message from the Editor-in-Chief

by Derek LeRoith, MD, PhD, FACE
Published 2015-01-01

Activating Transcription Factor-5 Knockdown Reduces Aggressiveness of Mammary Tumor Cells and Attenuates Mammary Tumor Growth

by Sarit Ben-Shmuel, Rola Rashed, Rola Rashed, Ran Rostoker, Elina Isakov, Zila Shen-Orr, Derek LeRoith, Derek LeRoith
Published 2017-07-01

The Role of Insulin and Insulin-like Growth Factors in the Increased Risk of Cancer in Diabetes

by Derek LeRoith, Eyal J. Scheinman, Keren Bitton-Worms
Published 2011-04-01

Deep sequencing of mRNA in CD24− and CD24+ mammary carcinoma Mvt1 cell line

by Ran Rostoker, Anitha D. Jayaprakash, Ravi Sachidanandam, Derek LeRoith
Published 2015-09-01

Insulin-like growth factors: Ligands, binding proteins, and receptors

by Derek LeRoith, Jeff M.P. Holly, Briony E. Forbes
Published 2021-10-01

Regulation of low-density lipoprotein receptor expression in triple negative breast cancer by EGFR-MAPK signaling

by Tiffany Scully, Nathan Kase, Emily J. Gallagher, Derek LeRoith
Published 2021-09-01

High-efficient FLPo deleter mice in C57BL/6J background.

by Yingjie Wu, Chunxin Wang, Hui Sun, Derek LeRoith, Shoshana Yakar
Published 2009-11-01

Intracerebroventricular leptin infusion improves glucose homeostasis in lean type 2 diabetic MKR mice via hepatic vagal and non-vagal mechanisms.

by Xiaosong Li, Xhiping Wu, Raul Camacho, Gary J Schwartz, Derek LeRoith
Published 2011-02-01

Two Closely Related Human Members of Chitinase-like Family, CHI3L1 and CHI3L2, Activate ERK1/2 in 293 and U373 Cells but Have the Different Influence on Cell Proliferation

by Pavlo O. Areshkov, Stanislav S. Avdieiev, Olena V. Balynska, Derek LeRoith, Vadym M. Kavsan
Published 2012-01-01

Multi-tissue computational modeling analyzes pathophysiology of type 2 diabetes in MKR mice.

by Amit Kumar, Thomas Harrelson, Nathan E Lewis, Emily J Gallagher, Derek LeRoith, Joseph Shiloach, Michael J Betenbaugh
Published 2014-01-01

Skeletal muscle growth hormone receptor signaling regulates basal, but not fasting-induced, lipid oxidation.

by Archana Vijayakumar, YingJie Wu, Nicholas J Buffin, Xiaosong Li, Hui Sun, Ronald E Gordon, Shoshana Yakar, Derek LeRoith
Published 2012-01-01

Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer

by Parijat Senapati, Hiroyuki Kato, Michael Lee, Amy Leung, Christine Thai, Angelica Sanchez, Emily J. Gallagher, Derek LeRoith, Victoria L. Seewaldt, David K. Ann, Dustin E. Schones
Published 2019-07-01

Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment

by Alison E. Obr, Sushil Kumar, Yun-Juan Chang, Joseph J. Bulatowicz, Betsy J. Barnes, Raymond B. Birge, Deborah A. Lazzarino, Emily Gallagher, Derek LeRoith, Teresa L. Wood
Published 2018-11-01

Hyperinsulinemia Promotes Esophageal Cancer Development in a Surgically-Induced Duodeno-Esophageal Reflux Murine Model

by Diletta Arcidiacono, Arben Dedja, Cinzia Giacometti, Matteo Fassan, Daniele Nucci, Simona Francia, Federico Fabris, Alice Zaramella, Emily J. Gallagher, Mauro Cassaro, Massimo Rugge, Derek LeRoith, Alfredo Alberti, Stefano Realdon
Published 2018-04-01

Insulin resistance contributes to racial disparities in breast cancer prognosis in US women

by Emily J. Gallagher, Kezhen Fei, Sheldon M. Feldman, Elisa Port, Neil B. Friedman, Susan K. Boolbol, Brigid Killelea, Melissa Pilewskie, Lydia Choi, Tari King, Anupma Nayak, Rebeca Franco, Daliz Cruz, Irini M. Antoniou, Derek LeRoith, Nina A. Bickell
Published 2020-05-01

Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis

by Liyuan Ran, Xiaoshuang Wang, Ai Mi, Yanshuang Liu, Jin Wu, Haoan Wang, Meihua Guo, Jie Sun, Bo Liu, Youwei Li, Dan Wang, Rujiao Jiang, Ning Wang, Wenting Gao, Li Zeng, Lin Huang, Xiaoli Chen, Derek LeRoith, Bin Liang, Xin Li, Yingjie Wu
Published 2019-06-01