Higher doses of naloxone are needed in the synthetic opioid era

by Ronald B. Moss, Dennis J. Carlo
Published 2019-02-01

Higher naloxone dosing in a quantitative systems pharmacology model that predicts naloxone-fentanyl competition at the opioid mu receptor level.

by Ronald B Moss, Meghan McCabe Pryor, Rebecca Baillie, Katherine Kudrycki, Christina Friedrich, Mike Reed, Dennis J Carlo
Published 2020-01-01

The Effects of Intramuscular Naloxone Dose on Mu Receptor Displacement of Carfentanil in Rhesus Monkeys

by Peter J. H. Scott, Robert A. Koeppe, Xia Shao, Melissa E. Rodnick, Alexandra R. Sowa, Bradford D. Henderson, Jenelle Stauff, Phillip S. Sherman, Janna Arteaga, Dennis J. Carlo, Ronald B. Moss
Published 2020-03-01