Binding-folding induced regulation of AF1 transactivation domain of the glucocorticoid receptor by a cofactor that binds to its DNA binding domain.

by Anna S Garza, Shagufta H Khan, Carmen M Moure, Dean P Edwards, Raj Kumar
Published 2011-01-01

Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer

by Uddalak Bharadwaj, Moses M. Kasembeli, T. Kris Eckols, Mikhail Kolosov, Paul Lang, Kurt Christensen, Dean P. Edwards, David J. Tweardy
Published 2014-09-01

Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

by Erin D. Giles, Sonali Jindal, Elizabeth A. Wellberg, Troy Schedin, Steven M. Anderson, Ann D. Thor, Dean P. Edwards, Paul S. MacLean, Pepper Schedin
Published 2018-06-01

Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers

by Jin-Ah Kim, Ying Tan, Xian Wang, Xixi Cao, Jamunarani Veeraraghavan, Yulong Liang, Dean P. Edwards, Shixia Huang, Xuewen Pan, Kaiyi Li, Rachel Schiff, Xiao-Song Wang
Published 2016-10-01

The Prognostic Impact of Intratumoral Aryl Hydrocarbon Receptor in Primary Breast Cancer Depends on the Type of Endocrine Therapy: A Population-Based Cohort Study

by Helga Tryggvadottir, Emma Sandén, Sofie Björner, Alessandra Bressan, Maria Ygland Rödström, Somayeh Khazaei, Dean P. Edwards, Björn Nodin, Karin Jirström, Karolin Isaksson, Karolin Isaksson, Signe Borgquist, Signe Borgquist, Helena Jernström
Published 2021-05-01

Proteomic Resistance Biomarkers for PI3K Inhibitor in Triple Negative Breast Cancer Patient-Derived Xenograft Models

by Zhanfang Guo, Tina Primeau, Jingqin Luo, Cynthia Zhang, Hua Sun, Jeremy Hoog, Feng Gao, Shixia Huang, Dean P. Edwards, Sherri R. Davies, Rebecca Aft, Li Ding, Matthew J. Ellis, Shunqiang Li, Cynthia X. Ma
Published 2020-12-01

TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiothe...

by Padmini Jayaraman, Falguni Parikh, Jared M. Newton, Aurelie Hanoteau, Charlotte Rivas, Rosemarie Krupar, Kimal Rajapakshe, Ravi Pathak, Kavin Kanthaswamy, Cassie MacLaren, Shixia Huang, Cristian Coarfa, Chad Spanos, Dean P. Edwards, Robin Parihar, Andrew G. Sikora
Published 2018-10-01

Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis.

by Patrick M McDonough, Dominique Maciejewski-Lenoir, Sean M Hartig, Rita A Hanna, Ross Whittaker, Andrew Heisel, James B Nicoll, Benjamin M Buehrer, Kurt Christensen, Maureen G Mancini, Michael A Mancini, Dean P Edwards, Jeffrey H Price
Published 2013-01-01

The Oncogenic STP Axis Promotes Triple-Negative Breast Cancer via Degradation of the REST Tumor Suppressor

by Kristen L. Karlin, Gourish Mondal, Jessica K. Hartman, Siddhartha Tyagi, Sarah J. Kurley, Chris S. Bland, Tiffany Y.T. Hsu, Alexander Renwick, Justin E. Fang, Ilenia Migliaccio, Celetta Callaway, Amritha Nair, Rocio Dominguez-Vidana, Don X. Nguyen, C. Kent Osborne, Rachel Schiff, Li-Yuan Yu-Lee, Sung Y. Jung, Dean P. Edwards, Susan G. Hilsenbeck, Jeffrey M. Rosen, Xiang H.-F. Zhang, Chad A. Shaw, Fergus J. Couch, Thomas F. Westbrook
Published 2014-11-01

Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer

by Akash K. Kaushik, Ali Shojaie, Katrin Panzitt, Rajni Sonavane, Harene Venghatakrishnan, Mohan Manikkam, Alexander Zaslavsky, Vasanta Putluri, Vihas T. Vasu, Yiqing Zhang, Ayesha S. Khan, Stacy Lloyd, Adam T. Szafran, Subhamoy Dasgupta, David A. Bader, Fabio Stossi, Hangwen Li, Susmita Samanta, Xuhong Cao, Efrosini Tsouko, Shixia Huang, Daniel E. Frigo, Lawrence Chan, Dean P. Edwards, Benny A. Kaipparettu, Nicholas Mitsiades, Nancy L. Weigel, Michael Mancini, Sean E. McGuire, Rohit Mehra, Michael M. Ittmann, Arul M. Chinnaiyan, Nagireddy Putluri, Ganesh S. Palapattu, George Michailidis, Arun Sreekumar
Published 2016-05-01