Antiviral therapy CD4+ T lymphocyte CD4-Positive T-Lymphocytes Cell Cycle Computational Biology Diagnosis Differentially expressed gene Drug Evaluation, Preclinical Drug discovery Drug screening Drug-targeting Gene set enrichment analysis Genes Humans Mitochondrial dysfunction Neuroendocrine tumors Perturbation techniques Phenotype Probability Transcriptome Transcriptomics Tumors biology cell cycle drug effect genetics human metabolism phenotype preclinical study