Novel Molecular Mechanisms in the Development of Non-Alcoholic Steatohepatitis

by Davide Povero, Ariel E. Feldstein
Published 2016-02-01

Microparticles release by adipocytes act as "find-me" signals to promote macrophage migration.

by Akiko Eguchi, Anny Mulya, Milos Lazic, Deepa Radhakrishnan, Michael P Berk, Davide Povero, Agnieszka Gornicka, Ariel E Feldstein
Published 2015-01-01

Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease.

by Davide Povero, Akiko Eguchi, Hongying Li, Casey D Johnson, Bettina G Papouchado, Alexander Wree, Karen Messer, Ariel E Feldstein
Published 2014-01-01

Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.

by Milos Lazic, Maria Eugenia Inzaugarat, Davide Povero, Iris C Zhao, Mark Chen, Madlena Nalbandian, Yury I Miller, Alejandra C Cherñavsky, Ariel E Feldstein, Dorothy D Sears
Published 2014-01-01

Lipid-Induced Hepatocyte-Derived Extracellular Vesicles Regulate Hepatic Stellate Cells via MicroRNA Targeting Peroxisome Proliferator-Activated Receptor-γSummary

by Davide Povero, Nadia Panera, Akiko Eguchi, Casey D. Johnson, Bettina G. Papouchado, Lucas de Araujo Horcel, Eva M. Pinatel, Anna Alisi, Valerio Nobili, Ariel E. Feldstein
Published 2015-11-01

Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis

by Daniel Cabrera, Alexander Wree, Davide Povero, Nancy Solís, Alejandra Hernandez, Margarita Pizarro, Han Moshage, Javiera Torres, Ariel E. Feldstein, Claudio Cabello-Verrugio, Enrique Brandan, Francisco Barrera, Juan Pablo Arab, Marco Arrese
Published 2017-06-01

Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH

by Davide Povero, Hirokazu Yamashita, Wenhua Ren, Mani G. Subramanian, Robert P. Myers, Akiko Eguchi, Douglas A. Simonetto, Zachary D. Goodman, Stephen A. Harrison, Arun J. Sanyal, Jaime Bosch, Ariel E. Feldstein
Published 2020-09-01

Microvesicles released from fat-laden cells promote activation of hepatocellular NLRP3 inflammasome: A pro-inflammatory link between lipotoxicity and non-alcoholic steatohepatitis.

by Stefania Cannito, Elisabetta Morello, Claudia Bocca, Beatrice Foglia, Elisa Benetti, Erica Novo, Fausto Chiazza, Mara Rogazzo, Roberto Fantozzi, Davide Povero, Salvatore Sutti, Elisabetta Bugianesi, Ariel E Feldstein, Emanuele Albano, Massimo Collino, Maurizio Parola
Published 2017-01-01