Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein–Protein Interactions

by Naomi S. Robertson, David R. Spring
Published 2018-04-01

Synthesis and Reactivity of a Bis-Strained Alkyne Derived from 1,1′-Biphenyl-2,2′,6,6′-tetrol

by Richard C. Knighton, Krishna Sharma, Naomi S. Robertson, David R. Spring, Martin Wills
Published 2019-01-01

Design and Synthesis of a Biotinylated Chemical Probe for Detecting the Molecular Targets of an Inhibitor of the Production of the Pseudomonas aeruginosa Virulence Factor Pyocyanin

by Ysobel R. Baker, Warren R. J. D. Galloway, James T. Hodgkinson, David R. Spring
Published 2013-09-01

Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products

by Stephen M. Geddis, Teodora Coroama, Suzanne Forrest, James T. Hodgkinson, Martin Welch, David R. Spring
Published 2018-10-01

Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections

by Sarah L. Kidd, Thomas J. Osberger, Natalia Mateu, Hannah F. Sore, David R. Spring
Published 2018-10-01

Two-directional synthesis as a tool for diversity-oriented synthesis: Synthesis of alkaloid scaffolds

by Kieron M. G. O’Connell, Monica Díaz-Gavilán, Warren R. J. D. Galloway, David R. Spring
Published 2012-06-01

Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study

by Eleanor L. Atkinson, Jessica Iegre, Paul D. Brear, Elizabeth A. Zhabina, Marko Hyvönen, David R. Spring
Published 2021-03-01

Identification of key residues that confer Rhodobacter sphaeroides LPS activity at horse TLR4/MD-2.

by Katherine L Irvine, Monique Gangloff, Catherine M Walsh, David R Spring, Nicholas J Gay, Clare E Bryant
Published 2014-01-01

Microscopy and chemical analyses reveal flavone-based woolly fibres extrude from micron-sized holes in glandular trichomes of Dionysia tapetodes

by Matthieu Bourdon, Josephine Gaynord, Karin H. Müller, Gareth Evans, Simon Wallis, Paul Aston, David R. Spring, Raymond Wightman
Published 2021-06-01

2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in <i>Pseudomonas aeruginosa</i>

by Alyssa C. McVey, Sean Bartlett, Mahmud Kajbaf, Annalisa Pellacani, Viviana Gatta, Päivi Tammela, David R. Spring, Martin Welch
Published 2020-04-01

(Z)-Selective Takai olefination of salicylaldehydes

by Stephen M. Geddis, Caroline E. Hagerman, Warren R. J. D. Galloway, Hannah F. Sore, Jonathan M. Goodman, David R. Spring
Published 2017-02-01

Combinatorial Synthesis of Structurally Diverse Triazole-Bridged Flavonoid Dimers and Trimers

by Tze Han Sum, Tze Jing Sum, Warren R. J. D. Galloway, Súil Collins, David G. Twigg, Florian Hollfelder, David R. Spring
Published 2016-09-01

Discovery of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells

by Bernardas Morkunas, Balint Gal, Warren R. J. D. Galloway, James T. Hodgkinson, Brett M. Ibbeson, Yaw Sing Tan, Martin Welch, David R. Spring
Published 2016-07-01

Antiplasmodial and trypanocidal activity of violacein and deoxyviolacein produced from synthetic operons

by Elizabeth Bilsland, Tatyana A. Tavella, Renata Krogh, Jamie E. Stokes, Annabelle Roberts, James Ajioka, David R. Spring, Adriano D. Andricopulo, Fabio T. M. Costa, Stephen G. Oliver
Published 2018-04-01