Pooled-Peptide Epitope Mapping Strategies Are Efficient and Highly Sensitive: An Evaluation of Methods for Identifying Human T Cell Epitope Specificities in Large-Scale HIV Vaccine...

by Andrew Fiore-Gartland, Bryce A Manso, David P Friedrich, Erin E Gabriel, Greg Finak, Zoe Moodie, Tomer Hertz, Stephen C De Rosa, Nicole Frahm, Peter B Gilbert, M Juliana McElrath
Published 2016-01-01

HIV-1 vaccine-induced T-cell responses cluster in epitope hotspots that differ from those induced in natural infection with HIV-1.

by Tomer Hertz, Hasan Ahmed, David P Friedrich, Danilo R Casimiro, Steven G Self, Lawrence Corey, M Juliana McElrath, Susan Buchbinder, Helen Horton, Nicole Frahm, Michael N Robertson, Barney S Graham, Peter Gilbert
Published 2013-01-01

MRKAd5 HIV-1 Gag/Pol/Nef vaccine-induced T-cell responses inadequately predict distance of breakthrough HIV-1 sequences to the vaccine or viral load.

by Holly Janes, Nicole Frahm, Allan DeCamp, Morgane Rolland, Erin Gabriel, Julian Wolfson, Tomer Hertz, Esper Kallas, Paul Goepfert, David P Friedrich, Lawrence Corey, James I Mullins, M Juliana McElrath, Peter Gilbert
Published 2012-01-01