FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts

by Markaisa Black, David Milewski, Tien Le, Xiaomeng Ren, Yan Xu, Vladimir V. Kalinichenko, Tanya V. Kalin
Published 2018-04-01

Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway.

by Chinmayee Goda, David Balli, Markaisa Black, David Milewski, Tien Le, Vladimir Ustiyan, Xiaomeng Ren, Vladimir V Kalinichenko, Tanya V Kalin
Published 2020-04-01

FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas.

by David Milewski, David Balli, Vladimir Ustiyan, Tien Le, Hendrik Dienemann, Arne Warth, Kai Breuhahn, Jeffrey A Whitsett, Vladimir V Kalinichenko, Tanya V Kalin
Published 2017-12-01

IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models.

by Anjelika Gasilina, Gurdat Premnauth, Purujit Gurjar, Jacek Biesiada, Shailaja Hegde, David Milewski, Gang Ma, Tanya V Kalin, Edward Merino, Jarek Meller, William Seibel, José A Cancelas, Lisa Privette Vinnedge, Nicolas N Nassar
Published 2020-01-01

Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma

by Silvia Pomella, Prethish Sreenivas, Berkley E. Gryder, Long Wang, David Milewski, Matteo Cassandri, Kunal Baxi, Nicole R. Hensch, Elena Carcarino, Young Song, Hsien-Chao Chou, Marielle E. Yohe, Benjamin Z. Stanton, Bruno Amadio, Ignazio Caruana, Cristiano De Stefanis, Rita De Vito, Franco Locatelli, Yidong Chen, Eleanor Y. Chen, Peter Houghton, Javed Khan, Rossella Rota, Myron S. Ignatius
Published 2021-01-01