Updating the Wnt pathways

by Jia Yu, David M. Virshup
Published 2014-10-01

Molecular Mechanisms Regulating Temperature Compensation of the Circadian Clock

by David M. Virshup, Rajesh Narasimamurthy
Published 2017-04-01

Site-specific phosphorylation of casein kinase 1 δ (CK1δ) regulates its activity towards the circadian regulator PER2.

by Gracie Wee Ling Eng, Edison, David M Virshup
Published 2017-01-01

Hematopoietic Wnts Modulate Endochondral Ossification During Fracture Healing

by Kenon Chua, Kenon Chua, Kenon Chua, Victor K. Lee, Cheri Chan, Andy Yew, Eric Yeo, David M. Virshup, David M. Virshup
Published 2021-05-01

Wnt traffic from endoplasmic reticulum to filopodia.

by Naushad Moti, Jia Yu, Gaelle Boncompain, Franck Perez, David M Virshup
Published 2019-01-01

Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer.

by Tracy M Covey, Kornelia Edes, Gary S Coombs, David M Virshup, Frank A Fitzpatrick
Published 2010-10-01

BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression

by Peng Xu, Elizabeth A. Raetz, Mayumi Kitagawa, David M. Virshup, Sang Hyun Lee
Published 2013-03-01

PORCN moonlights in a Wnt-independent pathway that regulates cancer cell proliferation.

by Tracy M Covey, Simran Kaur, Tina Tan Ong, Kyle D Proffitt, Yonghui Wu, Patrick Tan, David M Virshup
Published 2012-01-01

Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation

by Shiyang Liu, Nathan Harmston, Trudy Lee Glaser, Yunka Wong, Zheng Zhong, Babita Madan, David M. Virshup, Enrico Petretto
Published 2020-10-01

Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling

by Lucy Brunt, Gediminas Greicius, Sally Rogers, Benjamin D. Evans, David M. Virshup, Kyle C. A. Wedgwood, Steffen Scholpp
Published 2021-04-01

WNT inhibition creates a BRCA‐like state in Wnt‐addicted cancer

by Amanpreet Kaur, Jun Yi Stanley Lim, Sugunavathi Sepramaniam, Siddhi Patnaik, Nathan Harmston, May Ann Lee, Enrico Petretto, David M Virshup, Babita Madan
Published 2021-04-01

Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch

by Jonathan M Philpott, Rajesh Narasimamurthy, Clarisse G Ricci, Alfred M Freeberg, Sabrina R Hunt, Lauren E Yee, Rebecca S Pelofsky, Sarvind Tripathi, David M Virshup, Carrie L Partch
Published 2020-02-01

Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization

by Jiao Wang, Zhizhi Wang, Tingting Yu, Huan Yang, David M. Virshup, Geert J. P. L. Kops, Sang Hyun Lee, Weihong Zhou, Xin Li, Wenqing Xu, Zihe Rao
Published 2016-06-01

Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates

by Benjamin Mattes, Yonglong Dang, Gediminas Greicius, Lilian Tamara Kaufmann, Benedikt Prunsche, Jakob Rosenbauer, Johannes Stegmaier, Ralf Mikut, Suat Özbek, Gerd Ulrich Nienhaus, Alexander Schug, David M Virshup, Steffen Scholpp
Published 2018-07-01