Nucleolin participates in DNA double-strand break-induced damage response through MDC1-dependent pathway.

by Junya Kobayashi, Hiroko Fujimoto, Jun Sato, Ikue Hayashi, Sandeep Burma, Shinya Matsuura, David J Chen, Kenshi Komatsu
Published 2012-01-01

Nonenzymatic Role for WRN in Preserving Nascent DNA Strands after Replication Stress

by Fengtao Su, Shibani Mukherjee, Yanyong Yang, Eiichiro Mori, Souparno Bhattacharya, Junya Kobayashi, Steven M. Yannone, David J. Chen, Aroumougame Asaithamby
Published 2014-11-01

Histone Deacetylase Inhibitor Induced Radiation Sensitization Effects on Human Cancer Cells after Photon and Hadron Radiation Exposure

by Ariungerel Gerelchuluun, Junko Maeda, Eri Manabe, Colleen A. Brents, Takeji Sakae, Akira Fujimori, David J. Chen, Koji Tsuboi, Takamitsu A. Kato
Published 2018-02-01

The transcription factor TFII-I promotes DNA translesion synthesis and genomic stability.

by Farjana J Fattah, Kodai Hara, Kazi R Fattah, Chenyi Yang, Nan Wu, Ross Warrington, David J Chen, Pengbo Zhou, David A Boothman, Hongtao Yu
Published 2014-06-01

DNA Repair Deficient Chinese Hamster Ovary Cells Exhibiting Differential Sensitivity to Charged Particle Radiation under Aerobic and Hypoxic Conditions

by Ian M. Cartwright, Cathy Su, Jeremy S. Haskins, Victoria A. Salinas, Shigeaki Sunada, Hao Yu, Mitsuru Uesaka, Hirokazu Hirakawa, David J. Chen, Akira Fujimori, Takamitsu A. Kato
Published 2018-07-01

Differential radiosensitivity phenotypes of DNA-PKcs mutations affecting NHEJ and HRR systems following irradiation with gamma-rays or very low fluences of alpha particles.

by Yu-Fen Lin, Hatsumi Nagasawa, John B Little, Takamitsu A Kato, Hung-Ying Shih, Xian-Jin Xie, Paul F Wilson, John R Brogan, Akihiro Kurimasa, David J Chen, Joel S Bedford, Benjamin P C Chen
Published 2014-01-01

The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair.

by Hailong Wang, Linda Z Shi, Catherine C L Wong, Xuemei Han, Patty Yi-Hwa Hwang, Lan N Truong, Qingyuan Zhu, Zhengping Shao, David J Chen, Michael W Berns, John R Yates, Longchuan Chen, Xiaohua Wu
Published 2013-01-01