Analysis of morphological and neurochemical changes in subthalamic nucleus neurons in response to a unilateral 6-OHDA lesion of the substantia nigra in adult rats

by Katayoun Sedaghat, Andrew L. Gundlach, David I. Finkelstein
Published 2021-06-01

α-Synuclein E46K Mutation and Involvement of Oxidative Stress in a Drosophila Model of Parkinson’s Disease

by Samaneh Reiszadeh Jahromi, S. R. Ramesh, David I. Finkelstein, Mohammad Haddadi
Published 2021-01-01

Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function.

by Adam W Oaks, Maya Frankfurt, David I Finkelstein, Anita Sidhu
Published 2013-01-01

Trehalose improves traumatic brain injury-induced cognitive impairment.

by Stuart D Portbury, Dominic J Hare, David I Finkelstein, Paul A Adlard
Published 2017-01-01

Rescue of the Friedreich ataxia knockout mutation in transgenic mice containing an FXN-EGFP genomic reporter.

by Joseph P Sarsero, Timothy P Holloway, Lingli Li, David I Finkelstein, Panos A Ioannou
Published 2014-01-01

The Long Isoform of Intersectin-1 Has a Role in Learning and Memory

by Nakisa Malakooti, Melanie A. Pritchard, Feng Chen, Yong Yu, Charlotte Sgambelloni, Paul A. Adlard, David I. Finkelstein
Published 2020-02-01

Therapeutic potential of iron modulating drugs in a mouse model of multiple system atrophy

by Jay J. Shukla, Nadia Stefanova, Ashley I. Bush, Gawain McColl, David I. Finkelstein, Erin J. McAllum
Published 2021-11-01

Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse

by Peng Lei, Scott Ayton, Ambili Thoppuvalappil Appukuttan, Irene Volitakis, Paul A. Adlard, David I. Finkelstein, Ashley I. Bush
Published 2015-09-01

Metal chaperones prevent zinc-mediated cognitive decline

by Paul A. Adlard, Jacqui Parncutt, Varsha Lal, Simon James, Dominic Hare, Philip Doble, David I. Finkelstein, Ashley I. Bush
Published 2015-09-01

Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels.

by Jason Howitt, Amanda M Gysbers, Scott Ayton, Francine Carew-Jones, Ulrich Putz, David I Finkelstein, Glenda M Halliday, Seong-Seng Tan
Published 2014-01-01

Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson’s disease

by Dominic J Hare, Bárbara Rita Cardoso, Erika P Raven, Kay L Double, David I Finkelstein, Ewa A Szymlek-Gay, Beverley-Ann Biggs
Published 2017-01-01

Graphene Functionalized Scaffolds Reduce the Inflammatory Response and Supports Endogenous Neuroblast Migration when Implanted in the Adult Brain.

by Kun Zhou, Sepideh Motamed, George A Thouas, Claude C Bernard, Dan Li, Helena C Parkington, Harold A Coleman, David I Finkelstein, John S Forsythe
Published 2016-01-01

Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way

by He Xu, Veer B. Gupta, Ian J. Martins, Ralph N. Martins, Christopher J. Fowler, Ashley I. Bush, David I. Finkelstein, Paul A. Adlard
Published 2015-09-01

Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease.

by Paul A Adlard, Laura Bica, Anthony R White, Milawaty Nurjono, Gulay Filiz, Peter J Crouch, Paul S Donnelly, Roberto Cappai, David I Finkelstein, Ashley I Bush
Published 2011-01-01

Misfolded α-synuclein causes hyperactive respiration without functional deficit in live neuroblastoma cells

by Cathryn L. Ugalde, Sarah J. Annesley, Shane E. Gordon, Katelyn Mroczek, Matthew A. Perugini, Victoria A. Lawson, Paul R. Fisher, David I. Finkelstein, Andrew F. Hill
Published 2020-01-01

Migration and Differentiation of Neural Stem Cells Diverted From the Subventricular Zone by an Injectable Self-Assembling β-Peptide Hydrogel

by Sepideh Motamed, Sepideh Motamed, Mark P. Del Borgo, Kun Zhou, Ketav Kulkarni, Peter J. Crack, Tobias D. Merson, Marie-Isabel Aguilar, David I. Finkelstein, John S. Forsythe
Published 2019-11-01

Intravenous immunglobulin binds beta amyloid and modifies its aggregation, neurotoxicity and microglial phagocytosis in vitro.

by Susann Cattepoel, Alexander Schaub, Miriam Ender, Annette Gaida, Alain Kropf, Ursula Guggisberg, Marc W Nolte, Louis Fabri, Paul A Adlard, David I Finkelstein, Reinhard Bolli, Sylvia M Miescher
Published 2013-01-01

Distribution of Parkinson’s disease associated RAB39B in mouse brain tissue

by Yujing Gao, Gabrielle R. Wilson, Sarah E. M. Stephenson, Mustapha Oulad-Abdelghani, Nicolas Charlet-Berguerand, Kiymet Bozaoglu, Catriona A. McLean, Paul Q. Thomas, David I. Finkelstein, Paul J. Lockhart
Published 2020-03-01

The association of enteric neuropathy with gut phenotypes in acute and progressive models of Parkinson’s disease

by Rachel M. McQuade, Lewis M. Singleton, Hongyi Wu, Sophie Lee, Remy Constable, Madeleine Di Natale, Mitchell T. Ringuet, Joel P. Berger, Jessica Kauhausen, Clare L. Parish, David I. Finkelstein, John B. Furness, Shanti Diwakarla
Published 2021-04-01

The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s disease

by David I. Finkelstein, Jessica L. Billings, Paul A. Adlard, Scott Ayton, Amelia Sedjahtera, Colin L. Masters, Simon Wilkins, David M. Shackleford, Susan A. Charman, Wojciech Bal, Izabela A Zawisza, Ewa Kurowska, Andrew L. Gundlach, Sheri Ma, Ashley I. Bush, Dominic J. Hare, Philip A. Doble, Simon Crawford, Elisabeth CL. Gautier, Jack Parsons, Penny Huggins, Kevin J. Barnham, Robert A. Cherny
Published 2017-06-01