Biased versus Partial Agonism in the Search for Safer Opioid Analgesics

by Joaquim Azevedo Neto, Anna Costanzini, Roberto De Giorgio, David G. Lambert, Chiara Ruzza, Girolamo Calò
Published 2020-08-01

Properdin levels in human sepsis

by Cordula M Stover, John eMcDonald, Simon eByrne, David G Lambert, Jonathan eThompson
Published 2015-02-01

The Nociceptin/Orphanin FQ system is modulated in patients admitted to ICU with sepsis and after cardiopulmonary bypass.

by Jonathan P Thompson, Alcira Serrano-Gomez, John McDonald, Nadia Ladak, Sarah Bowrey, David G Lambert
Published 2013-01-01

Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Acti...

by Justyna Piekielna-Ciesielska, Roberto Artali, Ammar A.H. Azzam, David G. Lambert, Alicja Kluczyk, Luca Gentilucci, Anna Janecka
Published 2021-12-01

The nociceptin/orphanin FQ receptor antagonist UFP-101 reduces microvascular inflammation to lipopolysaccharide in vivo.

by Zoë L S Brookes, Emily N Stedman, Nicola J Brown, Christopher P Hebbes, Remo Guerrini, Girolamo Calo, Charles S Reilly, David G Lambert
Published 2013-01-01

Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo).

by Mark F Bird, Maria Camilla Cerlesi, Mark Brown, Davide Malfacini, Vanessa Vezzi, Paola Molinari, Laura Micheli, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Remo Guerrini, Girolamo Calò, David G Lambert
Published 2016-01-01