Kynurenine Pathway in Chronic Kidney Disease: What’s Old, What’s New, and What’s Next?

by Adrian Mor, Bartlomiej Kalaska, Dariusz Pawlak
Published 2020-09-01

Aryl hydrocarbon receptor (AhR) and its endogenous agonist – indoxyl sulfate in chronic kidney disease

by Tomasz Kamiński, Małgorzata Michałowska, Dariusz Pawlak
Published 2017-07-01

Paracrine Kynurenic Pathway Activation in the Bone of Young Uremic Rats Can Antagonize Anabolic Effects of PTH on Bone Turnover and Strength through the Disruption of PTH-Dependent...

by Krystyna Pawlak, Beata Sieklucka, Dariusz Pawlak
Published 2021-06-01

Kynurenines as a Novel Target for the Treatment of Malignancies

by Adrian Mor, Anna Tankiewicz-Kwedlo, Dariusz Pawlak
Published 2021-06-01

Role of Kynurenine Pathway in Oxidative Stress during Neurodegenerative Disorders

by Adrian Mor, Anna Tankiewicz-Kwedlo, Anna Krupa, Dariusz Pawlak
Published 2021-06-01

Oxidative Storm Induced by Tryptophan Metabolites: Missing Link between Atherosclerosis and Chronic Kidney Disease

by Iwona Kwiatkowska, Justyna M. Hermanowicz, Michal Mysliwiec, Dariusz Pawlak
Published 2020-01-01

Crosstalk between Tryptophan Metabolism via Kynurenine Pathway and Carbohydrate Metabolism in the Context of Cardio-Metabolic Risk—Review

by Małgorzata Kiluk, Janina Lewkowicz, Dariusz Pawlak, Anna Tankiewicz-Kwedlo
Published 2021-06-01

Not Only Immune Escape—The Confusing Role of the TRP Metabolic Pathway in Carcinogenesis

by Iwona Kwiatkowska, Justyna Magdalena Hermanowicz, Alicja Przybyszewska-Podstawka, Dariusz Pawlak
Published 2021-05-01

The involvement of AT2-receptor in the antithrombotic effect of losartan in renal hypertensive rats

by Ewa Chabielska, Tomasz Matys, Iwona Kucharewicz, Dariusz Pawlak, Roland Rólkowski, Wlodzimierz Buczko
Published 2000-09-01

The antithrombotic effect of angiotensin-(1—7) closely resembles that of losartan

by Iwona Kucharewicz, Ewa Chabielska, Dariusz Pawlak, Tomasz Matys, Roland Rólkowski, Wlodzimierz Buczko
Published 2000-09-01

The Uremic Toxin Indoxyl Sulfate Accelerates Thrombotic Response after Vascular Injury in Animal Models

by Malgorzata Karbowska, Tomasz W. Kaminski, Natalia Marcinczyk, Tomasz Misztal, Tomasz Rusak, Lukasz Smyk, Dariusz Pawlak
Published 2017-07-01

Preclinical Toxicity and Safety of MM-129—First-in-Class BTK/PD-L1 Inhibitor as a Potential Candidate against Colon Cancer

by Justyna Magdalena Hermanowicz, Bartlomiej Kalaska, Krystyna Pawlak, Beata Sieklucka, Joanna Miklosz, Mariusz Mojzych, Dariusz Pawlak
Published 2021-08-01

Modulation of the Paracrine Kynurenic System in Bone as a New Regulator of Osteoblastogenesis and Bone Mineral Status in an Animal Model of Chronic Kidney Disease Treated with LP53...

by Adrian Mor, Krystyna Pawlak, Bartlomiej Kalaska, Tomasz Domaniewski, Beata Sieklucka, Marta Zieminska, Bogdan Cylwik, Dariusz Pawlak
Published 2020-08-01

The concentration of kynurenine in rat model of asthma.

by Barbara Mroczko, Anna Tankiewicz-Kwedlo, Dariusz Pawlak, Irena Kasacka, Iwona Kucharewicz, Wlodzimierz Buczko, Anna Bodzenta-Lukaszyk
Published 2008-06-01

The Inhibitory Effect of Protamine on Platelets is Attenuated by Heparin without Inducing Thrombocytopenia in Rodents

by Joanna Miklosz, Bartlomiej Kalaska, Kamil Kaminski, Malgorzata Rusak, Krzysztof Szczubialka, Maria Nowakowska, Dariusz Pawlak, Andrzej Mogielnicki
Published 2019-09-01

Erythropoietin Intensifies the Proapoptotic Activity of LFM-A13 in Cells and in a Mouse Model of Colorectal Cancer

by Anna Tankiewicz-Kwedlo, Justyna Magdalena Hermanowicz, Krystyna Pawlak, Robert Czarnomysy, Krzysztof Bielawski, Izabela Prokop, Dariusz Pawlak
Published 2018-04-01

Response of Human Glioblastoma Cells to Vitamin B12 Deficiency: A Study Using the Non-Toxic Cobalamin Antagonist

by Zuzanna Rzepka, Jakub Rok, Mateusz Maszczyk, Artur Beberok, Justyna Magdalena Hermanowicz, Dariusz Pawlak, Dorota Gryko, Dorota Wrześniok
Published 2021-01-01

Cardiovascular and Respiratory Toxicity of Protamine Sulfate in Zebrafish and Rodent Models

by Joanna Miklosz, Bartlomiej Kalaska, Piotr Podlasz, Małgorzata Chmielewska-Krzesińska, Miłosz Zajączkowski, Adam Kosiński, Dariusz Pawlak, Andrzej Mogielnicki
Published 2021-03-01

MM-129 as a Novel Inhibitor Targeting PI3K/AKT/mTOR and PD-L1 in Colorectal Cancer

by Justyna Magdalena Hermanowicz, Krystyna Pawlak, Beata Sieklucka, Robert Czarnomysy, Iwona Kwiatkowska, Adam Kazberuk, Arkadiusz Surazynski, Mariusz Mojzych, Dariusz Pawlak
Published 2021-06-01

The Safety and Efficacy of the Repeated PRRT with [90Y]Y/[177Lu]Lu-DOTATATE in Patients with NET

by Anna Zemczak, Paweł Gut, Dariusz Pawlak, Maciej Kołodziej, Leszek Królicki, Beata Kos-Kudła, Marek Ruchała, Grzegorz Kamiński, Jolanta Kunikowska
Published 2021-01-01