The genotype of early-transmitting HIV gp120s promotes α (4) β(7)-reactivity, revealing α (4) β(7) +/CD4+ T cells as key targets in mucosal transmission.

by Fatima Nawaz, Claudia Cicala, Donald Van Ryk, Katharine E Block, Katija Jelicic, Jonathan P McNally, Olajumoke Ogundare, Massimiliano Pascuccio, Nikita Patel, Danlan Wei, Anthony S Fauci, James Arthos
Published 2011-02-01

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7.

by Sakaorat Lertjuthaporn, Claudia Cicala, Donald Van Ryk, Matthew Liu, Jason Yolitz, Danlan Wei, Fatima Nawaz, Allison Doyle, Brooke Horowitch, Chung Park, Shan Lu, Yang Lou, Shixia Wang, Ruimin Pan, Xunqing Jiang, Francois Villinger, Siddappa N Byrareddy, Philip J Santangelo, Lynn Morris, Constantinos Kurt Wibmer, Kristin Biris, Rosemarie D Mason, Jason Gorman, Joseph Hiatt, Elena Martinelli, Mario Roederer, Dai Fujikawa, Giacomo Gorini, Genoveffa Franchini, Anush Arakelyan, Aftab A Ansari, Kovit Pattanapanyasat, Xiang-Peng Kong, Anthony S Fauci, James Arthos
Published 2018-08-01