Challenges in drug discovery targeting TriTryp diseases with an emphasis on leishmaniasis

by Laura M. Alcântara, Thalita C.S. Ferreira, Fernanda R. Gadelha, Danilo C. Miguel
Published 2018-12-01

Tamoxifen is effective in the treatment of Leishmania amazonensis infections in mice.

by Danilo C Miguel, Jenicer K U Yokoyama-Yasunaka, Silvia R B Uliana
Published 2008-01-01

Leishmania-mediated inhibition of iron export promotes parasite replication in macrophages.

by Rym Ben-Othman, Andrew R Flannery, Danilo C Miguel, Diane M Ward, Jerry Kaplan, Norma W Andrews
Published 2014-01-01

The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania amazonensis.

by Rebecca L Renberg, Xiaojing Yuan, Tamika K Samuel, Danilo C Miguel, Iqbal Hamza, Norma W Andrews, Andrew R Flannery
Published 2015-05-01

Heme uptake by Leishmania amazonensis is mediated by the transmembrane protein LHR1.

by Chau Huynh, Xiaojing Yuan, Danilo C Miguel, Rebecca L Renberg, Olga Protchenko, Caroline C Philpott, Iqbal Hamza, Norma W Andrews
Published 2012-01-01

Antileishmanial activity of the estrogen receptor modulator raloxifene.

by Juliana Q Reimão, Danilo C Miguel, Noemi N Taniwaki, Cristiana T Trinconi, Jenicer K U Yokoyama-Yasunaka, Silvia R B Uliana
Published 2014-05-01

Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania

by Cristiana T. Trinconi, Danilo C. Miguel, Ariel M. Silber, Christopher Brown, John G.M. Mina, Paul W. Denny, Norton Heise, Silvia R.B. Uliana
Published 2018-12-01

Unveiling the Kinomes of Leishmania infantum and L. braziliensis Empowers the Discovery of New Kinase Targets and Antileishmanial Compounds

by Joyce V.B. Borba, Arthur C. Silva, Pablo I.P. Ramos, Nathalia Grazzia, Danilo C. Miguel, Eugene N. Muratov, Nicholas Furnham, Carolina H. Andrade
Published 2019-01-01