Increased functional stability and homogeneity of viral envelope spikes through directed evolution.

by Daniel P Leaman, Michael B Zwick
Published 2013-02-01

Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization.

by Arthur S Kim, Daniel P Leaman, Michael B Zwick
Published 2014-07-01

Functional stability of unliganded envelope glycoprotein spikes among isolates of human immunodeficiency virus type 1 (HIV-1).

by Nitish Agrawal, Daniel P Leaman, Eric Rowcliffe, Heather Kinkead, Raman Nohria, Junya Akagi, Katherine Bauer, Sean X Du, Robert G Whalen, Dennis R Burton, Michael B Zwick
Published 2011-01-01

Prime-boost immunization of rabbits with HIV-1 gp120 elicits potent neutralization activity against a primary viral isolate.

by Kristin M Narayan, Nitish Agrawal, Sean X Du, Janelle E Muranaka, Katherine Bauer, Daniel P Leaman, Pham Phung, Kay Limoli, Helen Chen, Rebecca I Boenig, Terri Wrin, Michael B Zwick, Robert G Whalen
Published 2013-01-01

Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile

by Edurne Rujas, Daniel P. Leaman, Sara Insausti, Pablo Carravilla, Miguel García-Porras, Eneko Largo, Izaskun Morillo, Rubén Sánchez-Eugenia, Lei Zhang, Hong Cui, Ibon Iloro, Félix Elortza, Jean-Philippe Julien, Christian Eggeling, Michael B. Zwick, Jose M.M. Caaveiro, José L. Nieva
Published 2021-09-01

An MPER antibody neutralizes HIV-1 using germline features shared among donors

by Lei Zhang, Adriana Irimia, Lingling He, Elise Landais, Kimmo Rantalainen, Daniel P. Leaman, Thomas Vollbrecht, Armando Stano, Daniel I. Sands, Arthur S. Kim, IAVI Protocol G Investigators, Pascal Poignard, Dennis R. Burton, Ben Murrell, Andrew B. Ward, Jiang Zhu, Ian A. Wilson, Michael B. Zwick
Published 2019-11-01