Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4.

by Paulina Kasperkiewicz, Marcin Poreba, Scott J Snipas, S Jack Lin, Daniel Kirchhofer, Guy S Salvesen, Marcin Drag
Published 2015-01-01

Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif

by Mark Ultsch, Michael J. Holliday, Stefan Gerhardy, Paul Moran, Suzie J. Scales, Nidhi Gupta, Francesca Oltrabella, Cecilia Chiu, Wayne Fairbrother, Charles Eigenbrot, Daniel Kirchhofer
Published 2021-07-01

Inhibition of Angiopoietin-2 Production by Myofibrocytes Inhibits Neointimal Hyperplasia After Endoluminal Injury in Mice

by Daxin Chen, Ke Li, El-Li Tham, Lin-Lin Wei, Ning Ma, Philippa C. Dodd, Yi Luo, Daniel Kirchhofer, John H. McVey, Anthony Dorling
Published 2018-07-01

Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge

by Henry R. Maun, Rajesh Vij, Benjamin T. Walters, Ashley Morando, Janet K. Jackman, Ping Wu, Alberto Estevez, Xiaocheng Chen, Yvonne Franke, Michael T. Lipari, Mark S. Dennis, Daniel Kirchhofer, Claudio Ciferri, Kelly M. Loyet, Tangsheng Yi, Charles Eigenbrot, Robert A. Lazarus, James T. Koerber
Published 2020-12-01

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes

by David S. Hewings, Johanna Heideker, Taylur P. Ma, Andrew P. AhYoung, Farid El Oualid, Alessia Amore, Gregory T. Costakes, Daniel Kirchhofer, Bradley Brasher, Thomas Pillow, Nataliya Popovych, Till Maurer, Carsten Schwerdtfeger, William F. Forrest, Kebing Yu, John Flygare, Matthew Bogyo, Ingrid E. Wertz
Published 2018-03-01