Synthesis and Sulfur Electrophilicity of the Nuphar Thiaspirane Pharmacophore

by Norihiro Tada, Daniel J. Jansen, Matthew P. Mower, Megan M. Blewett, Jeffrey C. Umotoy, Benjamin F. Cravatt, Dennis W. Wolan, Ryan A. Shenvi
Published 2016-06-01

KDM5 histone demethylases repress immune response via suppression of STING.

by Lizhen Wu, Jian Cao, Wesley L Cai, Sabine M Lang, John R Horton, Daniel J Jansen, Zongzhi Z Liu, Jocelyn F Chen, Meiling Zhang, Bryan T Mott, Katherine Pohida, Ganesha Rai, Stephen C Kales, Mark J Henderson, Xin Hu, Ajit Jadhav, David J Maloney, Anton Simeonov, Shu Zhu, Akiko Iwasaki, Matthew D Hall, Xiaodong Cheng, Gerald S Shadel, Qin Yan
Published 2018-08-01