Membrane Compartmentalization and Scaffold Proteins in Leukocyte Migration

by Guerric P. B. Samson, Daniel F. Legler, Daniel F. Legler, Daniel F. Legler
Published 2020-04-01

New insights in chemokine signaling [version 1; referees: 3 approved]

by Daniel F. Legler, Marcus Thelen
Published 2018-01-01

Role of Mechanotransduction and Tension in T Cell Function

by Jérémie Rossy, Jérémie Rossy, Julia M. Laufer, Daniel F. Legler, Daniel F. Legler
Published 2018-11-01

ACKR4 Recruits GRK3 Prior to β-Arrestins but Can Scavenge Chemokines in the Absence of β-Arrestins

by Christoph Matti, Angela Salnikov, Marc Artinger, Gianluca D'Agostino, Ilona Kindinger, Mariagrazia Uguccioni, Marcus Thelen, Daniel F. Legler, Daniel F. Legler, Daniel F. Legler
Published 2020-04-01

CAL-1 as Cellular Model System to Study CCR7-Guided Human Dendritic Cell Migration

by Edith Uetz-von Allmen, Guerric P. B. Samson, Guerric P. B. Samson, Vladimir Purvanov, Takahiro Maeda, Daniel F. Legler, Daniel F. Legler, Daniel F. Legler
Published 2021-09-01

CCR7 Is Recruited to the Immunological Synapse, Acts as Co-stimulatory Molecule and Drives LFA-1 Clustering for Efficient T Cell Adhesion Through ZAP70

by Julia M. Laufer, Julia M. Laufer, Ilona Kindinger, Marc Artinger, Marc Artinger, Andreas Pauli, Daniel F. Legler, Daniel F. Legler
Published 2019-01-01

In vivo TCR signaling in CD4+ T cells imprints a cell-intrinsic, transient low motility pattern independent of chemokine receptor expression levels or microtubular network, integri...

by Markus eAckerknecht, Mark A Hauser, Daniel F Legler, Jens Volker Stein
Published 2015-06-01

A Versatile Toolkit for Semi-Automated Production of Fluorescent Chemokines to Study CCR7 Expression and Functions

by Marc Artinger, Christoph Matti, Oliver J. Gerken, Christopher T. Veldkamp, Daniel F. Legler
Published 2021-04-01

Fluorescently Tagged CCL19 and CCL21 to Monitor CCR7 and ACKR4 Functions

by Vladimir Purvanov, Christoph Matti, Guerric P. B. Samson, Ilona Kindinger, Daniel F. Legler
Published 2018-12-01

Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation

by Julia M. Laufer, Mark A. Hauser, Ilona Kindinger, Vladimir Purvanov, Andreas Pauli, Daniel F. Legler
Published 2019-10-01

Loss of Gadkin Affects Dendritic Cell Migration In Vitro.

by Hannah Schachtner, Mirjana Weimershaus, Vanessa Stache, Natalia Plewa, Daniel F Legler, Uta E Höpken, Tanja Maritzen
Published 2015-01-01

Engineering of Nanobodies Recognizing the Human Chemokine Receptor CCR7

by Barbara D. Jakobs, Lisa Spannagel, Vladimir Purvanov, Edith Uetz-von Allmen, Christoph Matti, Daniel F. Legler
Published 2019-05-01

β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4

by Gianluca D’Agostino, Marc Artinger, Massimo Locati, Massimo Locati, Laurent Perez, Daniel F. Legler, Daniel F. Legler, Marco E. Bianchi, Curzio Rüegg, Marcus Thelen, Adriano Marchese, Marco B. L. Rocchi, Valentina Cecchinato, Mariagrazia Uguccioni, Mariagrazia Uguccioni
Published 2020-09-01

Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

by Astrid S. Jørgensen, Olav Larsen, Edith Uetz-von Allmen, Michael Lückmann, Daniel F. Legler, Thomas M. Frimurer, Christopher T. Veldkamp, Gertrud M. Hjortø, Mette M. Rosenkilde
Published 2019-09-01

CXCL14 Preferentially Synergizes With Homeostatic Chemokine Receptor Systems

by Ariadni Kouzeli, Paul J. Collins, Mieke Metzemaekers, Max Meyrath, Martyna Szpakowska, Marc Artinger, Sofie Struyf, Paul Proost, Andy Chevigne, Daniel F. Legler, Matthias Eberl, Bernhard Moser
Published 2020-10-01

B cell zone reticular cell microenvironments shape CXCL13 gradient formation

by Jason Cosgrove, Mario Novkovic, Stefan Albrecht, Natalia B. Pikor, Zhaoukun Zhou, Lucas Onder, Urs Mörbe, Jovana Cupovic, Helen Miller, Kieran Alden, Anne Thuery, Peter O’Toole, Rita Pinter, Simon Jarrett, Emily Taylor, Daniel Venetz, Manfred Heller, Mariagrazia Uguccioni, Daniel F. Legler, Charles J. Lacey, Andrew Coatesworth, Wojciech G. Polak, Tom Cupedo, Bénedicte Manoury, Marcus Thelen, Jens V. Stein, Marlene Wolf, Mark C. Leake, Jon Timmis, Burkhard Ludewig, Mark C. Coles
Published 2020-07-01