Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer’s Disease Therapy

by Lazhar Zribi, Irene Pachòn-Angona, Òscar M. Bautista-Aguilera, Daniel Diez-Iriepa, José Marco-Contelles, Lhassane Ismaili, Isabel Iriepa, Fakher Chabchoub
Published 2020-07-01

Homo-Tris-Nitrones Derived from α-Phenyl-<i>N-tert</i>-butylnitrone: Synthesis, Neuroprotection and Antioxidant Properties

by Daniel Diez-Iriepa, Beatriz Chamorro, Marta Talaván, Mourad Chioua, Isabel Iriepa, Dimitra Hadjipavlou-Litina, Francisco López-Muñoz, José Marco-Contelles, María Jesús Oset-Gasque
Published 2020-10-01

Synthesis, Neuroprotection, and Antioxidant Activity of 1,1′-Biphenylnitrones as α-Phenyl-<i>N-tert</i>-Butylnitrone Analogues in In Vitro Ischemia Models

by Beatriz Chamorro, David García-Vieira, Daniel Diez-Iriepa, Estíbaliz Garagarza, Mourad Chioua, Dimitra Hadjipavlou-Litina, Francisco López-Muñoz, José Marco-Contelles, María Jesús Oset-Gasque
Published 2021-02-01

Privileged Quinolylnitrones for the Combined Therapy of Ischemic Stroke and Alzheimer’s Disease

by José M. Alonso, Alejandro Escobar-Peso, Alejandra Palomino-Antolín, Daniel Diez-Iriepa, Mourad Chioua, Emma Martínez-Alonso, Isabel Iriepa, Javier Egea, Alberto Alcázar, José Marco-Contelles
Published 2021-08-01

QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer’s Disease Therapy

by Eva Ramos, Alejandra Palomino-Antolín, Manuela Bartolini, Isabel Iriepa, Ignacio Moraleda, Daniel Diez-Iriepa, Abdelouahid Samadi, Carol V. Cortina, Mourad Chioua, Javier Egea, Alejandro Romero, José Marco-Contelles
Published 2019-04-01

Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy

by Irene Pachón-Angona, Bernard Refouvelet, Rudolf Andrýs, Helène Martin, Vincent Luzet, Isabel Iriepa, Ignacio Moraleda, Daniel Diez-Iriepa, María-Jesús Oset-Gasque, José Marco-Contelles, Kamil Musilek, Lhassane Ismaili
Published 2019-01-01