Metabolic adaptations to hypoxia in the neonatal mouse forebrain can occur independently of the transporters SLC7A5 and SLC3A2

by Eamon Fitzgerald, Jennie Roberts, Daniel A. Tennant, James P. Boardman, Amanda J. Drake
Published 2021-04-01

DiME: a scalable disease module identification algorithm with application to glioma progression.

by Yunpeng Liu, Daniel A Tennant, Zexuan Zhu, John K Heath, Xin Yao, Shan He
Published 2014-01-01

High-Speed Tracer Analysis of Metabolism (HS-TrAM) [version 2; referees: 2 approved, 2 approved with reservations]

by Thomas Brendan Smith, Kamlesh Patel, Haydn Munford, Andrew Peet, Daniel A. Tennant, Mark Jeeves, Christian Ludwig
Published 2018-08-01

High-Speed Tracer Analysis of Metabolism (HS-TrAM) [version 1; referees: 1 approved, 2 approved with reservations]

by Thomas Brendan Smith, Kamlesh Patel, Haydn Munford, Andrew Peet, Daniel A. Tennant, Mark Jeeves, Christian Ludwig
Published 2018-01-01

Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival.

by Christian Frezza, Liang Zheng, Daniel A Tennant, Dmitri B Papkovsky, Barbara A Hedley, Gabriela Kalna, David G Watson, Eyal Gottlieb
Published 2011-01-01

Metabolomic perfusate analysis during kidney machine perfusion: the pig provides an appropriate model for human studies.

by Jay Nath, Alison Guy, Thomas B Smith, Mark Cobbold, Nicholas G Inston, James Hodson, Daniel A Tennant, Christian Ludwig, Andrew R Ready
Published 2014-01-01

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD+ depletion [version 2; peer review: 2 approved]

by Lucy A. Oakey, Rachel S. Fletcher, Yasir S. Elhassan, David M. Cartwright, Craig L. Doig, Antje Garten, Alpesh Thakker, Oliver D. K. Maddocks, Tong Zhang, Daniel A. Tennant, Christian Ludwig, Gareth G. Lavery
Published 2019-09-01

Intracellular sodium elevation reprograms cardiac metabolism

by Dunja Aksentijević, Anja Karlstaedt, Marina V. Basalay, Brett A. O’Brien, David Sanchez-Tatay, Seda Eminaga, Alpesh Thakker, Daniel A. Tennant, William Fuller, Thomas R. Eykyn, Heinrich Taegtmeyer, Michael J. Shattock
Published 2020-08-01

Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction

by Craig L. Doig, Agnieszka E. Zielinska, Rachel S. Fletcher, Lucy A. Oakey, Yasir S. Elhassan, Antje Garten, David Cartwright, Silke Heising, Ahmed Alsheri, David G. Watson, Cornelia Prehn, Jerzy Adamski, Daniel A. Tennant, Gareth G. Lavery
Published 2020-02-01

Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours

by Christopher D. Bennett, Sarah E. Kohe, Simrandip K. Gill, Nigel P. Davies, Martin Wilson, Lisa C. D. Storer, Timothy Ritzmann, Simon M. L. Paine, Ian S. Scott, Ina Nicklaus-Wollenteit, Daniel A. Tennant, Richard G. Grundy, Andrew C. Peet
Published 2018-08-01

A human pluripotent stem cell model for the analysis of metabolic dysfunction in hepatic steatosis

by Matthew C. Sinton, Jose Meseguer-Ripolles, Baltasar Lucendo-Villarin, Sara Wernig-Zorc, John P. Thomson, Roderick N. Carter, Marcus J. Lyall, Paul D. Walker, Alpesh Thakker, Richard R. Meehan, Gareth G. Lavery, Nicholas M. Morton, Christian Ludwig, Daniel A. Tennant, David C. Hay, Amanda J. Drake
Published 2021-01-01

A Role for Cytosolic Fumarate Hydratase in Urea Cycle Metabolism and Renal Neoplasia

by Julie Adam, Ming Yang, Christina Bauerschmidt, Mitsuhiro Kitagawa, Linda O’Flaherty, Pratheesh Maheswaran, Gizem Özkan, Natasha Sahgal, Dilair Baban, Keiko Kato, Kaori Saito, Keiko Iino, Kaori Igarashi, Michael Stratford, Christopher Pugh, Daniel A. Tennant, Christian Ludwig, Benjamin Davies, Peter J. Ratcliffe, Mona El-Bahrawy, Houman Ashrafian, Tomoyoshi Soga, Patrick J. Pollard
Published 2013-05-01

Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis

by Kate E.R. Hollinshead, Haydn Munford, Katherine L. Eales, Chiara Bardella, Chunjie Li, Cristina Escribano-Gonzalez, Alpesh Thakker, Yannic Nonnenmacher, Katarina Kluckova, Mark Jeeves, Robert Murren, Federica Cuozzo, Dan Ye, Giulio Laurenti, Wei Zhu, Karsten Hiller, David J. Hodson, Wei Hua, Ian P. Tomlinson, Christian Ludwig, Ying Mao, Daniel A. Tennant
Published 2018-03-01

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

by Yasir S. Elhassan, Katarina Kluckova, Rachel S. Fletcher, Mark S. Schmidt, Antje Garten, Craig L. Doig, David M. Cartwright, Lucy Oakey, Claire V. Burley, Ned Jenkinson, Martin Wilson, Samuel J.E. Lucas, Ildem Akerman, Alex Seabright, Yu-Chiang Lai, Daniel A. Tennant, Peter Nightingale, Gareth A. Wallis, Konstantinos N. Manolopoulos, Charles Brenner, Andrew Philp, Gareth G. Lavery
Published 2019-08-01