A Tryptophan ‘Gate’ in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity

by Liu He, Zoe Jelić Matošević, Damjan Mitić, Dora Markulin, Tom Killelea, Marija Matković, Branimir Bertoša, Ivana Ivančić-Baće, Edward L. Bolt
Published 2021-03-01