Lack of Interleukin-6 Affects IFN-γ and TNF-α Production and Early In Vivo Control of <i>Brucella abortus</i> Infection

by Erika S. Guimarães, Jéssica M. Martins, Marco Túlio R. Gomes, Daiane M. Cerqueira, Sergio C. Oliveira
Published 2020-12-01

Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome.

by Danielle P A Mascarenhas, Daiane M Cerqueira, Marcelo S F Pereira, Fernanda V S Castanheira, Talita D Fernandes, Graziele Z Manin, Larissa D Cunha, Dario S Zamboni
Published 2017-08-01

Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection.

by Daiane M Cerqueira, Marco Túlio R Gomes, Alexandre L N Silva, Marcella Rungue, Natan R G Assis, Erika S Guimarães, Suellen B Morais, Petr Broz, Dario S Zamboni, Sergio C Oliveira
Published 2018-12-01