Screening of Chorioamnionitis Using Volatile Organic Compound Detection in Exhaled Breath: A Pre-clinical Proof of Concept Study

by Daan R. M. G. Ophelders, Daan R. M. G. Ophelders, Agnes W. Boots, Agnes W. Boots, Matthias C. Hütten, Salwan Al-Nasiry, Salwan Al-Nasiry, Reint K. Jellema, Owen B. Spiller, Frederik-Jan van Schooten, Frederik-Jan van Schooten, Agnieszka Smolinska, Agnieszka Smolinska, Tim G. A. M. Wolfs, Tim G. A. M. Wolfs
Published 2021-05-01

Global Hypoxia-Ischemia Induced Inflammation and Structural Changes in the Preterm Ovine Gut Which Were Not Ameliorated by Mesenchymal Stem Cell Treatment

by Maria Nikiforou, Carolin Willburger, Anja E de Jong, Nico Kloosterboer, Reint K Jellema, Daan R M G Ophelders, Harry W M Steinbusch, Boris W Kramer, Tim G A M Wolfs
Published 2016-04-01

Annexin A1 as Neuroprotective Determinant for Blood-Brain Barrier Integrity in Neonatal Hypoxic-Ischemic Encephalopathy

by Ruth Gussenhoven, Luise Klein, Daan R. M. G. Ophelders, Denise H. J. Habets, Bernd Giebel, Boris W. Kramer, Leon J. Schurgers, Chris P. M. Reutelingsperger, Tim G. A. M. Wolfs
Published 2019-01-01

Preterm Brain Injury, Antenatal Triggers, and Therapeutics: Timing Is Key

by Daan R.M.G. Ophelders, Ruth Gussenhoven, Luise Klein, Reint K. Jellema, Rob J.J. Westerlaken, Matthias C. Hütten, Jeroen Vermeulen, Guido Wassink, Alistair J. Gunn, Tim G.A.M. Wolfs
Published 2020-08-01

New surfactant with SP-B and C analogs gives survival benefit after inactivation in preterm lambs.

by Matthias Seehase, Jennifer J P Collins, Elke Kuypers, Reint K Jellema, Daan R M G Ophelders, Olga L Ospina, J Perez-Gil, Federico Bianco, Raffaella Garzia, Roberta Razzetti, Boris W Kramer
Published 2012-01-01

Mesenchymal Stromal Cell‐Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia‐Ischemia

by Daan R.M.G. Ophelders, Tim G.A.M. Wolfs, Reint K. Jellema, Alex Zwanenburg, Peter Andriessen, Tammo Delhaas, Anna-Kristin Ludwig, Stefan Radtke, Vera Peters, Leon Janssen, Bernd Giebel, Boris W. Kramer
Published 2016-06-01

ST waveform analysis for monitoring hypoxic distress in fetal sheep after prolonged umbilical cord occlusion.

by Peter Andriessen, Alex Zwanenburg, Judith O E H van Laar, Rik Vullings, Ben J M Hermans, Hendrik J Niemarkt, Reint K Jellema, Daan R M G Ophelders, Tim G A M Wolfs, Boris W Kramer, Tammo Delhaas
Published 2018-01-01

Mesenchymal stem cells induce T-cell tolerance and protect the preterm brain after global hypoxia-ischemia.

by Reint K Jellema, Tim G A M Wolfs, Valéria Lima Passos, Alex Zwanenburg, Daan R M G Ophelders, Elke Kuypers, Anton H N Hopman, Jeroen Dudink, Harry W Steinbusch, Peter Andriessen, Wilfred T V Germeraad, Joris Vanderlocht, Boris W Kramer
Published 2013-01-01

Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus

by Ruth Gussenhoven, Rob J. J. Westerlaken, Daan R. M. G. Ophelders, Alan H. Jobe, Matthew W. Kemp, Suhas G. Kallapur, Luc J. Zimmermann, Per T. Sangild, Stanislava Pankratova, Pierre Gressens, Boris W. Kramer, Bobbi Fleiss, Tim G. A. M. Wolfs
Published 2018-04-01

Sequential Exposure to Antenatal Microbial Triggers Attenuates Alveolar Growth and Pulmonary Vascular Development and Impacts Pulmonary Epithelial Stem/Progenitor Cells

by Helene Widowski, Helene Widowski, Helene Widowski, Niki L. Reynaert, Niki L. Reynaert, Daan R. M. G. Ophelders, Daan R. M. G. Ophelders, Matthias C. Hütten, Matthias C. Hütten, Peter G. J. Nikkels, Carmen A. H. Severens-Rijvers, Jack P. M. Cleutjens, Jack P. M. Cleutjens, Matthew W. Kemp, John P. Newnham, Masatoshi Saito, Masatoshi Saito, Haruo Usuda, Haruo Usuda, Matthew S. Payne, Alan H. Jobe, Alan H. Jobe, Boris W. Kramer, Boris W. Kramer, Boris W. Kramer, Tammo Delhaas, Tammo Delhaas, Tim G. A. M. Wolfs, Tim G. A. M. Wolfs
Published 2021-02-01

Effects of intra-amniotic lipopolysaccharide and maternal betamethasone on brain inflammation in fetal sheep.

by Elke Kuypers, Reint K Jellema, Daan R M G Ophelders, Jeroen Dudink, Maria Nikiforou, Tim G A M Wolfs, Ilias Nitsos, J Jane Pillow, Graeme R Polglase, Matthew W Kemp, Masatoshi Saito, John P Newnham, Alan H Jobe, Suhas G Kallapur, Boris W Kramer
Published 2013-01-01