Generation and initial characterization of FDD knock in mice.

by Luca Giliberto, Shuji Matsuda, Ruben Vidal, Luciano D'Adamio, Luciano D'Adamio
Published 2009-11-01

Inhibition of γ-secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia

by Tamayev Robert, D’Adamio Luciano
Published 2012-04-01

APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesic...

by Dolores Del Prete, Franco Lombino, Xinran Liu, Luciano D'Adamio, Luciano D'Adamio
Published 2014-01-01

An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss.

by Franco Lombino, Fabrizio Biundo, Robert Tamayev, Ottavio Arancio, Luciano D'Adamio, Luciano D'Adamio
Published 2013-01-01

The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function.

by Alessia P M Barbagallo, Zilai Wang, Hui Zheng, Luciano D'Adamio, Luciano D'Adamio
Published 2011-03-01

Transgenic expression of the amyloid-beta precursor protein-intracellular domain does not induce Alzheimer's Disease-like traits in vivo.

by Luca Giliberto, Cristina d'Abramo, Christopher Michael Acker, Peter Davies, Luciano D'Adamio, Luciano D'Adamio
Published 2010-07-01

CD74 interacts with APP and suppresses the production of Aβ

by D'Adamio Luciano, Matsuda Yukiko, Matsuda Shuji
Published 2009-10-01

β - but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia

by Tamayev Robert, Matsuda Shuji, D’Adamio Luciano
Published 2012-02-01

The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains

by D'Adamio Luciano, Zhou Dawang, Tamayev Robert
Published 2009-07-01

Significance of Blood and Cerebrospinal Fluid Biomarkers for Alzheimer’s Disease: Sensitivity, Specificity and Potential for Clinical Use

by Cristina d’Abramo, Luciano D’Adamio, Luca Giliberto
Published 2020-09-01

Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo.

by Alessia P M Barbagallo, Richard Weldon, Robert Tamayev, Dawang Zhou, Luca Giliberto, Oded Foreman, Luciano D'Adamio, Luciano D'Adamio
Published 2010-11-01

Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation

by Marc D Tambini, Kelly A Norris, Luciano D'Adamio
Published 2020-02-01

Spotlight on brodalumab in the treatment of plaque psoriasis: the evidence to date

by Galluzzo M, D'Adamio S, Massaro A, Piccolo A, Bianchi L, Talamonti M
Published 2019-05-01

Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection

by Tamayev Robert, Akpan Nsikan, Arancio Ottavio, Troy Carol M, D’Adamio Luciano
Published 2012-12-01

Proteomic Characterization of a Mouse Model of Familial Danish Dementia

by Monica Vitale, Giovanni Renzone, Shuji Matsuda, Andrea Scaloni, Luciano D'Adamio, Nicola Zambrano
Published 2012-01-01

APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses

by Tomas Fanutza, Dolores Del Prete, Michael J Ford, Pablo E Castillo, Luciano D’Adamio
Published 2015-11-01

Silver-Coated Hip Megaprosthesis in Oncological Limb Savage Surgery

by F. Donati, G. Di Giacomo, S. D’Adamio, A. Ziranu, S. Careri, MA. Rosa, G. Maccauro
Published 2016-01-01

Microglia TREM2R47H Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels

by Siqiang Ren, Wen Yao, Marc D Tambini, Tao Yin, Kelly A Norris, Luciano D'Adamio
Published 2020-06-01

Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role

by De Luca Pasquale, Tamagno Elena, Weldon Richard, Zhou Dawang, Giliberto Luca, Tabaton Massimo, D'Adamio Luciano
Published 2008-09-01

Innovative Management of Wheel-Rail Adhesion Conditions in Localization Algorithms for the Automatic Train Protection

by G. Vettori, B. Allotta, M. Malvezzi, L. Pugi, A. Ridolfi, P. D’Adamio, F. Salotti, L. Landi
Published 2013-07-01