Design, Synthesis, and In Vitro Biological Activities of a Bio-Oxidizable Prodrug to Deliver Both ChEs and DYRK1A Inhibitors for AD Therapy

by Anaïs Barré, Rabah Azzouz, Vincent Gembus, Cyril Papamicaël, Vincent Levacher
Published 2019-04-01

Dihydroquinoline Carbamate DQS1-02 as a Prodrug of a Potent Acetylcholinesterase Inhibitor for Alzheimer’s Disease Therapy: Multigram-Scale Synthesis, Mechanism Investigations, in...

by Florent Alix, Vincent Gembus, Laurent Coquet, Marie Hubert-Roux, Philippe Chan, Lina Truong, Muriel Sebban, Gaël Coadou, Hassan Oulyadi, Cyril Papamicaël, Vincent Levacher
Published 2018-12-01