Administration, Topical Adrenergic Antagonists Antihypertensive Agents Carbonic Anhydrase Inhibitors Clinical Trials as Topic Evidence-Based Medicine Glaucoma Humans Neuroprotective Agents Prostaglandins adrenergic receptor blocking agent antihypertensive agent carbonate dehydratase inhibitor clinical trial (topic) conference paper evidence based medicine glaucoma human methodology neuroprotection neuroprotective agent pathophysiology pharmacological approach prostaglandin topical drug administration