A subset of epithelial cells mimics regulatory T cells and contributes to immune evasion during development of pancreatic adenocarcinoma

by Courtney W. Houchen, Min Li
Published 2020-06-01

Cancer Stem Cell Marker DCLK1 Correlates with Tumorigenic Immune Infiltrates in the Colon and Gastric Adenocarcinoma Microenvironments

by Xiangyan Wu, Dongfeng Qu, Nathaniel Weygant, Jun Peng, Courtney W. Houchen
Published 2020-01-01

Tuft and Cancer Stem Cell Marker DCLK1: A New Target to Enhance Anti-Tumor Immunity in the Tumor Microenvironment

by Zhiyun Cao, Nathaniel Weygant, Parthasarathy Chandrakesan, Courtney W. Houchen, Jun Peng, Dongfeng Qu
Published 2020-12-01

Elevated doublecortin-like kinase 1 serum levels revert to baseline after therapy in early stage esophageal adenocarcinoma

by Emily M. Christman, Parthasarathy Chandrakesan, Nathaniel Weygant, John T. Maple, William M. Tierney, Kenneth J. Vega, Courtney W. Houchen
Published 2019-03-01

RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells.

by Dharmalingam Subramaniam, Satish Ramalingam, David C Linehan, Brian K Dieckgraefe, Russell G Postier, Courtney W Houchen, Roy A Jensen, Shrikant Anant
Published 2011-02-01

Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis.

by Dongfeng Qu, Nathaniel Weygant, Randal May, Parthasarathy Chandrakesan, Mohammad Madhoun, Naushad Ali, Sripathi M Sureban, Guangyu An, Michael J Schlosser, Courtney W Houchen
Published 2015-01-01

DCLK1 Monoclonal Antibody-Based CAR-T Cells as a Novel Treatment Strategy against Human Colorectal Cancers

by Sripathi M. Sureban, Robert Berahovich, Hua Zhou, Shirley Xu, Lijun Wu, Kai Ding, Randal May, Dongfeng Qu, Edwin Bannerman-Menson, Vita Golubovskaya, Courtney W. Houchen
Published 2019-12-01

Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury.

by Sripathi M Sureban, Randal May, Dongfeng Qu, Parthasarathy Chandrakesan, Nathaniel Weygant, Naushad Ali, Stan A Lightfoot, Kai Ding, Shahid Umar, Michael J Schlosser, Courtney W Houchen
Published 2015-01-01

DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer.

by Sripathi M Sureban, Randal May, Dongfeng Qu, Nathaniel Weygant, Parthasarathy Chandrakesan, Naushad Ali, Stan A Lightfoot, Panayotis Pantazis, Chinthalapally V Rao, Russell G Postier, Courtney W Houchen
Published 2013-01-01

Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer

by Dongfeng Qu, Nathaniel Weygant, Jiannan Yao, Parthasarathy Chandrakesan, William L. Berry, Randal May, Kamille Pitts, Sanam Husain, Stan Lightfoot, Min Li, Timothy C. Wang, Guangyu An, Cynthia Clendenin, Ben Z. Stanger, Courtney W. Houchen
Published 2019-01-01

Correction: Fluvastatin Interferes with Hepatitis C Virus Replication via Microtubule Bundling and a Doublecortin-like Kinase-Mediated Mechanism

by Naushad Ali, Heba Allam, Ted Bader, Randal May, Kanthesh M. Basalingappa, William L. Berry, Parthasarathy Chandrakesan, Dongfeng Qu, Nathaniel Weygant, Michael S. Bronze, Shahid Umar, Ralf Janknecht, Sripathi M. Sureban, Mark Huycke, Courtney W. Houchen
Published 2013-01-01

Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism.

by Naushad Ali, Heba Allam, Ted Bader, Randal May, Kanthesh M Basalingappa, William L Berry, Parthasarathy Chandrakesan, Dongfeng Qu, Nathaniel Weygant, Michael S Bronze, Shahid Umar, Ralf Janknecht, Sripathi M Sureban, Mark Huycke, Courtney W Houchen
Published 2013-01-01

Correction: Fluvastatin Interferes with Hepatitis C Virus Replication via Microtubule Bundling and a Doublecortin-like Kinase-Mediated Mechanism.

by Naushad Ali, Heba Allam, Ted Bader, Randal May, Kanthesh M. Basalingappa, William L. Berry, Parthasarathy Chandrakesan, Dongfeng Qu, Nathaniel Weygant, Michael S. Bronze, Shahid Umar, Ralf Janknecht, Sripathi M. Sureban, Mark Huycke, Courtney W. Houchen
Published 2013-01-01

An integrated model of N6-methyladenosine regulators to predict tumor aggressiveness and immune evasion in pancreatic cancer

by Zhijun Zhou, Junxia Zhang, Chao Xu, Jingxuan Yang, Yuqing Zhang, Mingyang Liu, Xiuhui Shi, Xiaoping Li, Hanxiang Zhan, Wei Chen, Lacey R. McNally, Kar-Ming Fung, Wenyi Luo, Courtney W. Houchen, Yulong He, Changhua Zhang, Min Li
Published 2021-03-01

Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells.

by Dongfeng Qu, Jeremy Johnson, Parthasarathy Chandrakesan, Nathaniel Weygant, Randal May, Nicole Aiello, Andrew Rhim, Lichao Zhao, Wei Zheng, Stanley Lightfoot, Shubham Pant, Jeremy Irvan, Russell Postier, James Hocker, Jay S Hanas, Naushad Ali, Sripathi M Sureban, Guangyu An, Michael J Schlosser, Ben Stanger, Courtney W Houchen
Published 2015-01-01