CRISPR Genome Editing: How to Make a Fantastic Method Even Better

by Cord Brakebusch
Published 2021-02-01

Rho GTPase Signaling in Health and Disease: A Complex Signaling Network

by Cord Brakebusch
Published 2021-02-01

Improving Precise CRISPR Genome Editing by Small Molecules: Is there a Magic Potion?

by Nadja Bischoff, Sandra Wimberger, Marcello Maresca, Cord Brakebusch
Published 2020-05-01

ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation

by Rafael Brandao, Mei Qi Kwa, Yossi Yarden, Cord Brakebusch
Published 2021-06-01

RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis

by Alba Manresa-Arraut, Flemming Fryd Johansen, Cord Brakebusch, Shohreh Issazadeh-Navikas, Henrik Hasseldam
Published 2018-05-01

MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model

by Mei Qi Kwa, Rafael Brandao, Trong H. Phung, Jianfeng Ge, Giuseppe Scieri, Cord Brakebusch
Published 2021-04-01

Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion.

by Aleksandra Piwko-Czuchra, Heidi Koegel, Hannelore Meyer, Martina Bauer, Sabine Werner, Cord Brakebusch, Reinhard Fässler
Published 2009-01-01

RhoA regulates the quiescence and cell fate of skeletal stem and progenitor cells (SSPCs)

by Dana Trompet, Marian Dejaeger, Marion Mesnieres, Elena Nefyodova, Ruben Cardoen, Cord Brakebusch, Jos Tournoy, Frank Luyten, Christa Maes
Published 2020-10-01

Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency

by Javier Martin Gonzalez, Sophie M. Morgani, Robert A. Bone, Kasper Bonderup, Sahar Abelchian, Cord Brakebusch, Joshua M. Brickman
Published 2016-08-01

Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

by Martin Wahlestedt, Eva Erlandsson, Trine Kristiansen, Rong Lu, Cord Brakebusch, Irving L. Weissman, Joan Yuan, Javier Martin-Gonzalez, David Bryder
Published 2017-02-01

The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells

by Ana C. Martins Cavaco, Maryam Rezaei, Michele F. Caliandro, Augusto Martins Lima, Martin Stehling, Sameer A. Dhayat, Jörg Haier, Cord Brakebusch, Johannes A. Eble
Published 2018-12-01

ATF3 downmodulates its new targets IFI6 and IFI27 to suppress the growth and migration of tongue squamous cell carcinoma cells.

by Lin Xu, Tingjian Zu, Tao Li, Min Li, Jun Mi, Fuxiang Bai, Guanyi Liu, Jie Wen, Hui Li, Cord Brakebusch, Xuxia Wang, Xunwei Wu
Published 2021-02-01

Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway

by Tingjian Zu, Tingjian Zu, Jie Wen, Jie Wen, Lin Xu, Lin Xu, Lin Xu, Hui Li, Jun Mi, Jun Mi, Hui Li, Cord Brakebusch, David E. Fisher, Xunwei Wu, Xunwei Wu, Xunwei Wu
Published 2020-04-01

Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

by Murali K. Akula, Mohamed X. Ibrahim, Emil G. Ivarsson, Omar M. Khan, Israiel T. Kumar, Malin Erlandsson, Christin Karlsson, Xiufeng Xu, Mikael Brisslert, Cord Brakebusch, Donghai Wang, Maria Bokarewa, Volkan I. Sayin, Martin O. Bergo
Published 2019-09-01

Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation

by Hui Li, Qi Yao, Alberto Garcia Mariscal, Xudong Wu, Justus Hülse, Esben Pedersen, Kristian Helin, Ari Waisman, Caroline Vinkel, Simon Francis Thomsen, Alexandra Avgustinova, Salvador Aznar Benitah, Paola Lovato, Hanne Norsgaard, Mette Sidsel Mortensen, Lone Veng, Björn Rozell, Cord Brakebusch
Published 2018-04-01

FMNL formins boost lamellipodial force generation

by Frieda Kage, Moritz Winterhoff, Vanessa Dimchev, Jan Mueller, Tobias Thalheim, Anika Freise, Stefan Brühmann, Jana Kollasser, Jennifer Block, Georgi Dimchev, Matthias Geyer, Hans-Joachim Schnittler, Cord Brakebusch, Theresia E. B. Stradal, Marie-France Carlier, Michael Sixt, Josef Käs, Jan Faix, Klemens Rottner
Published 2017-03-01

A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

by Sebastian Dütting, Frederique Gaits-Iacovoni, David Stegner, Michael Popp, Adrien Antkowiak, Judith M.M. van Eeuwijk, Paquita Nurden, Simon Stritt, Tobias Heib, Katja Aurbach, Oguzhan Angay, Deya Cherpokova, Niels Heinz, Ayesha A. Baig, Maximilian G. Gorelashvili, Frank Gerner, Katrin G. Heinze, Jerry Ware, Georg Krohne, Zaverio M. Ruggeri, Alan T. Nurden, Harald Schulze, Ute Modlich, Irina Pleines, Cord Brakebusch, Bernhard Nieswandt
Published 2017-06-01