Rev-erbα heterozygosity produces a dose-dependent phenotypic advantage in mice.

by Ryan D Welch, Cyrielle Billon, Amina Kameric, Thomas P Burris, Colin A Flaveny
Published 2020-01-01

The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis

by Kristine Griffett, Ryan D. Welch, Colin A. Flaveny, Grant R. Kolar, Brent A. Neuschwander-Tetri, Thomas P. Burris
Published 2015-04-01

A two-hit model of alcoholic liver disease that exhibits rapid, severe fibrosis.

by Monideepa Sengupta, Suomia Abuirqeba, Amina Kameric, Aurore Cecile-Valfort, Arindam Chatterjee, Kristine Griffett, Thomas P Burris, Colin A Flaveny
Published 2021-01-01

Rev-Erb co-regulates muscle regeneration via tethered interaction with the NF-Y cistrome

by Ryan D. Welch, Chun Guo, Monideepa Sengupta, Katherine J. Carpenter, Natalie A. Stephens, Stacy A. Arnett, Marvin J. Meyers, Lauren M. Sparks, Steven R. Smith, Jinsong Zhang, Thomas P. Burris, Colin A. Flaveny
Published 2017-07-01

Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis.

by Bin Li, Colin A Flaveny, Camilla Giambelli, Dennis Liang Fei, Lu Han, Brian I Hang, Feng Bai, Xin-Hai Pei, Vania Nose, Oname Burlingame, Anthony J Capobianco, Darren Orton, Ethan Lee, David J Robbins
Published 2014-01-01

CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition

by Adele M. Musicant, Kshitij Parag-Sharma, Weida Gong, Monideepa Sengupta, Arindam Chatterjee, Erin C. Henry, Yi-Hsuan Tsai, Michele C. Hayward, Siddharth Sheth, Renee Betancourt, Trevor G. Hackman, Ricardo J. Padilla, Joel S. Parker, Jimena Giudice, Colin A. Flaveny, David N. Hayes, Antonio L. Amelio
Published 2021-02-01