Does acute treatment of dapagliflozin reduce cardiac infarct size through direct cardiac effects or reductions in blood glucose levels?

by Coert J. Zuurbier
Published 2020-09-01

Editorial: Diabetes and Heart Failure: Pathogenesis and Novel Therapeutic Approaches

by Claudio de Lucia, Celestino Sardu, Laurent Metzinger, Coert J. Zuurbier
Published 2019-03-01

Cardioprotecive Properties of Known Agents in Rat Ischemia-Reperfusion Model Under Clinically Relevant Conditions: Only the NAD Precursor Nicotinamide Riboside Reduces Infarct Size...

by Yang Xiao, Philippa Phelp, Qian Wang, Diane Bakker, Rianne Nederlof, Markus W. Hollmann, Coert J. Zuurbier
Published 2021-08-01

A randomized trial of remote ischemic preconditioning and control treatment for cardioprotection in sevoflurane-anesthetized CABG patients

by Rianne Nederlof, Nina C. Weber, Nicole P. Juffermans, Bas A. M. J. de Mol, Markus W. Hollmann, Benedikt Preckel, Coert J. Zuurbier
Published 2017-03-01

Sodium Glucose Co-Transporter 2 Inhibitors Ameliorate Endothelium Barrier Dysfunction Induced by Cyclic Stretch through Inhibition of Reactive Oxygen Species

by Xiaoling Li, Gregor Römer, Raphaela P. Kerindongo, Jeroen Hermanides, Martin Albrecht, Markus W. Hollmann, Coert J. Zuurbier, Benedikt Preckel, Nina C. Weber
Published 2021-06-01

Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signaling.

by Coert J Zuurbier, Willeke M C Jong, Otto Eerbeek, Anneke Koeman, Wilco P Pulskens, Loes M Butter, Jaklien C Leemans, Markus W Hollmann
Published 2012-01-01

Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients

by Laween Uthman, Antonius Baartscheer, Cees A. Schumacher, Jan W. T. Fiolet, Marius C. Kuschma, Markus W. Hollmann, Ruben Coronel, Ruben Coronel, Nina C. Weber, Coert J. Zuurbier
Published 2018-11-01

Empagliflozin Decreases Lactate Generation in an NHE-1 Dependent Fashion and Increases α-Ketoglutarate Synthesis From Palmitate in Type II Diabetic Mouse Hearts

by Hong Zhang, Hong Zhang, Laween Uthman, Diane Bakker, Sahinda Sari, Sha Chen, Markus W. Hollmann, Ruben Coronel, Nina C. Weber, Sander M. Houten, Michel van Weeghel, Michel van Weeghel, Coert J. Zuurbier
Published 2020-12-01

NLRX1 Deletion Increases Ischemia-Reperfusion Damage and Activates Glucose Metabolism in Mouse Heart

by Hong Zhang, Hong Zhang, Yang Xiao, Rianne Nederlof, Diane Bakker, Pengbo Zhang, Stephen E. Girardin, Markus W. Hollmann, Nina C. Weber, Sander M. Houten, Michel van Weeghel, Richard G. Kibbey, Coert J. Zuurbier
Published 2020-12-01

Empagliflozin and Dapagliflozin Reduce ROS Generation and Restore NO Bioavailability in Tumor Necrosis Factor α-Stimulated Human Coronary Arterial Endothelial Cells

by Laween Uthman, Anna Homayr, Rio P. Juni, Eva L. Spin, Raphaela Kerindongo, Marleen Boomsma, Markus W. Hollmann, Benedikt Preckel, Pieter Koolwijk, Victor W.M. van Hinsbergh, Coert J. Zuurbier, Martin Albrecht, Nina C. Weber
Published 2019-11-01