Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections

by Wilson, J. A., Dancik, V., Muller, S., Wagner, B. K., Schreiber, S. L., Clemons, Paul A, Carrinski, Hyman, Koehler, Angela Nicole
Published 2018

Quantitative-Proteomic Comparison of Alpha and Beta Cells to Uncover Novel Targets for Lineage Reprogramming

by Choudhary, Amit, Hu He, Kaihui, Mertins, Philipp, Udeshi, Namrata D., Dancik, Vlado, Fomina-Yadlin, Dina, Kubicek, Stefan, Clemons, Paul A., Schreiber, Stuart L., Wagner, Bridget K., Carr, Steven A
Published 2014

Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells

by Kubicek, Stefan, Gilbert, Joshua C., Fomina-Yadlin, Dina, Gitlin, Alexander D., Yuan, Yuan, Wagner, Florence F., Holson, Edward B., Luo, Tuoping, Lewis, Timothy A., Taylor, Bradley, Gupta, Supriya, Shamji, Alykhan F., Wagner, Bridget K., Clemons, Paul A., Schreiber, Stuart L.
Published 2012

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

by Kuo, Szu-Yu, Castoreno, Adam B., Aldrich, Leslie N., Lassen, Kara G., Goel, Gautam, Dancik, Vlado, Kuballa, Petric, Latorre, Isabel, Conway, Kara L., Sarkar, Sovan, Maetzel, Dorothea, Jaenisch, Rudolf, Clemons, Paul A., Schreiber, Stuart L., Shamji, Alykhan F., Xavier, Ramnik J.
Published 2016

Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics

by de Waal, Luc, Lewis, Timothy A, Rees, Matthew G, Tsherniak, Aviad, Wu, Xiaoyun, Choi, Peter S, Gechijian, Lara, Hartigan, Christina, Faloon, Patrick W, Hickey, Mark J, Tolliday, Nicola, Carr, Steven A, Clemons, Paul A, Munoz, Benito, Wagner, Bridget K, Shamji, Alykhan F, Schenone, Monica, Burgin, Alex B, Schreiber, Stuart L, Greulich, Heidi, Meyerson, Matthew, Koehler, Angela Nicole
Published 2017

DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets

by Hanaford, A. R., Price, A., Kahlert, U. D., Maciaczyk, J., Nikkhah, G., Dancik, V., Seashore-Ludlow, B., Viswanathan, V., Rees, M. G., Eberhart, C. G., Raabe, E. H., Archer, Tenley, Kim, Jong Wook, Ehrenberger, Tobias, Clemons, Paul A, Stewart, Michelle L., Shamji, Alykhan, Fraenkel, Ernest, Pomeroy, Scott L., Tamayo, Pablo, Schreiber, Stuart L., Mesirov, Jill P.
Published 2018

Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription

by Struntz, Nicholas B., Chen, Andrew I, Deutzmann, Anja, Wilson, Robert M., Stefan, Eric, Evans, Helen L, Ramirez, Maricela A., Liang, Tong, Caballero, Francisco, Wildschut, Mattheus H.E, Neel, Dylan V, Freeman, David B., Pop, Marius S, McConkey, Marie, Muller, Sandrine, Curtin, Brice Harrison, Tseng, Hanna, Frombach, Kristen R., Butty, Vincent L G, Levine, Stuart S., Feau, Clementine, Elmiligy, Sarah, Hong, Jiyoung A., Lewis, Timothy A., Vetere, Amedeo, Clemons, Paul A., Malstrom, Scott E., Ebert, Benjamin L., Lin, Charles Y., Felsher, Dean W., Koehler, Angela Nicole
Published 2020