Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaB.

by Nadine Rohwer, Christof Dame, Anja Haugstetter, Bertram Wiedenmann, Katharina Detjen, Clemens A Schmitt, Thorsten Cramer
Published 2010-01-01

Neutropenic Sepsis in the ICU: Outcome Predictors in a Two-Phase Model and Microbiology Findings

by Jan M. Kruse, Thomas Jenning, Sibylle Rademacher, Renate Arnold, Clemens A. Schmitt, Achim Jörres, Philipp Enghard, Michael Oppert
Published 2016-01-01

The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.

by Rukeia El-Athman, Nikolai N Genov, Jeannine Mazuch, Kaiyang Zhang, Yong Yu, Luise Fuhr, Mónica Abreu, Yin Li, Thomas Wallach, Achim Kramer, Clemens A Schmitt, Angela Relógio
Published 2017-12-01

Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice.

by Armin Gerbitz, Madhusudhanan Sukumar, Florian Helm, Andrea Wilke, Christian Friese, Cornelia Fahrenwaldt, Frank M Lehmann, Christoph Loddenkemper, Thomas Kammertoens, Josef Mautner, Clemens A Schmitt, Thomas Blankenstein, Georg W Bornkamm
Published 2012-01-01

Local and Central Evaluation of HER2 Positivity and Clinical Outcome in Advanced Gastric and Gastroesophageal Cancer—Results from the AGMT GASTRIC-5 Registry

by Florian Huemer, Lukas Weiss, Peter Regitnig, Thomas Winder, Bernd Hartmann, Josef Thaler, Gudrun Piringer, Clemens A. Schmitt, Wolfgang Eisterer, Hannes Gänzer, Alois Wüstner, Johannes Andel, Björn Jagdt, Hanno Ulmer, Richard Greil, Ewald Wöll
Published 2020-03-01

H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients

by Kolja Schleich, Julia Kase, Jan R. Dörr, Saskia Trescher, Animesh Bhattacharya, Yong Yu, Elizabeth M. Wailes, Dorothy N. Y. Fan, Philipp Lohneis, Maja Milanovic, Andrea Lau, Dido Lenze, Michael Hummel, Bjoern Chapuy, Ulf Leser, Maurice Reimann, Soyoung Lee, Clemens A. Schmitt
Published 2020-07-01

MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I

by Johannes Brägelmann, Carina Lorenz, Sven Borchmann, Kazuya Nishii, Julia Wegner, Lydia Meder, Jenny Ostendorp, David F. Ast, Alena Heimsoeth, Takamasa Nakasuka, Atsuko Hirabae, Sachi Okawa, Marcel A. Dammert, Dennis Plenker, Sebastian Klein, Philipp Lohneis, Jianing Gu, Laura K. Godfrey, Jan Forster, Marija Trajkovic-Arsic, Thomas Zillinger, Mareike Haarmann, Alexander Quaas, Stefanie Lennartz, Marcel Schmiel, Joshua D’Rozario, Emily S. Thomas, Henry Li, Clemens A. Schmitt, Julie George, Roman K. Thomas, Silvia von Karstedt, Gunther Hartmann, Reinhard Büttner, Roland T. Ullrich, Jens T. Siveke, Kadoaki Ohashi, Martin Schlee, Martin L. Sos
Published 2021-09-01