A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans

by Nicholas R Jones, Melissa A Pegues, Mark A McCrory, Walter Singleton, Claudette Bethune, Brenda F Baker, Daniel A Norris, Rosanne M Crooke, Mark J Graham, Alexander J Szalai
Published 2012-01-01

PK/PD modeling of FXI antisense oligonucleotides to bridge the dose‐FXI activity relation from healthy volunteers to end‐stage renal disease patients

by Stefan Willmann, Eleonora Marostica, Nelleke Snelder, Alexander Solms, Markus Jensen, Maximilian Lobmeyer, Anthonie W. A. Lensing, Claudette Bethune, Erin Morgan, Rosie Z. Yu, Yanfeng Wang, Shiangtung W. Jung, Richard Geary, Sanjay Bhanot
Published 2021-08-01