A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses.

by Timothy Gatheral, Daniel M Reed, Laura Moreno, Peter J Gough, Bart J Votta, Clark A Sehon, David J Rickard, John Bertin, Eric Lim, Andrew G Nicholson, Jane A Mitchell
Published 2012-01-01

MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates

by Yves Dondelinger, Wim Declercq, Sylvie Montessuit, Ria Roelandt, Amanda Goncalves, Inge Bruggeman, Paco Hulpiau, Kathrin Weber, Clark A. Sehon, Robert W. Marquis, John Bertin, Peter J. Gough, Savvas Savvides, Jean-Claude Martinou, Mathieu J.M. Bertrand, Peter Vandenabeele
Published 2014-05-01

Identification of selective small molecule inhibitors of the nucleotide-binding oligomerization domain 1 (NOD1) signaling pathway.

by David J Rickard, Clark A Sehon, Viera Kasparcova, Lorena A Kallal, Pamela A Haile, Xin Zeng, Monica N Montoute, Derek D Poore, Hu Li, Zining Wu, Patrick M Eidam, John G Emery, Robert W Marquis, Peter J Gough, John Bertin
Published 2014-01-01

Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway.

by David J Rickard, Clark A Sehon, Viera Kasparcova, Lorena A Kallal, Xin Zeng, Monica N Montoute, Tushar Chordia, Derek D Poore, Hu Li, Zining Wu, Patrick M Eidam, Pamela A Haile, Jong Yu, John G Emery, Robert W Marquis, Peter J Gough, John Bertin
Published 2013-01-01