Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against Mycobacterium tuberculosis

by Michelle M. Bellerose, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Thomas R. Ioerger, Christopher M. Sassetti
Published 2020-08-01

Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression

by Siddharth Subramaniyam, Michael A. DeJesus, Anisha Zaveri, Clare M. Smith, Richard E. Baker, Sabine Ehrt, Dirk Schnappinger, Christopher M. Sassetti, Thomas R. Ioerger
Published 2019-11-01

TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2.

by Joseph D Trimarco, Brook E Heaton, Ryan R Chaparian, Kaitlyn N Burke, Raquel A Binder, Gregory C Gray, Clare M Smith, Vineet D Menachery, Nicholas S Heaton
Published 2021-05-01

Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice

by Clare M. Smith, Megan K. Proulx, Rocky Lai, Michael C. Kiritsy, Timothy A. Bell, Pablo Hock, Fernando Pardo-Manuel de Villena, Martin T. Ferris, Richard E. Baker, Samuel M. Behar, Christopher M. Sassetti
Published 2019-11-01

Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy

by Michelle M. Bellerose, Seung-Hun Baek, Chuan-Chin Huang, Caitlin E. Moss, Eun-Ik Koh, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Jong Seok Lee, Seokyong Eum, Sung Jae Shin, Sang-Nae Cho, Megan Murray, Christopher M. Sassetti
Published 2019-07-01

Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype

by Clare M. Smith, Megan K. Proulx, Andrew J. Olive, Dominick Laddy, Bibhuti B. Mishra, Caitlin Moss, Nuria Martinez Gutierrez, Michelle M. Bellerose, Palmira Barreira-Silva, Jia Yao Phuah, Richard E. Baker, Samuel M. Behar, Hardy Kornfeld, Thomas G. Evans, Gillian Beamer, Christopher M. Sassetti
Published 2016-09-01